ArticleJournal of veterinary internal medicine2020
Tracheal microbial populations in horses with moderate asthma.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
- The Microbiota and Equine Asthma: An Integrative View of the Gut-Lung Axis.Animals : an open access journal from MDPI · 2024Review
- Increased freedom of head movement mitigates stress and bacterial load in the airways of horses during transport.Frontiers in veterinary science · 2024Article
- Survey of the approach to the diagnosis and management of bacterial pneumonia in adult horses by equine veterinarians.Frontiers in veterinary science · 2024Article
- Topography of the respiratory, oral, and guttural pouch bacterial and fungal microbiotas in horses.Journal of veterinary internal medicine · 2023Article
- The Immune Mechanisms of Severe Equine Asthma-Current Understanding and What Is Missing.Animals : an open access journal from MDPI · 2022Review
- The Semen Microbiome and Semen Parameters in Healthy Stallions.Animals : an open access journal from MDPI · 2022Article
- Mycoplasmas as Host Pantropic and Specific Pathogens: Clinical Implications, Gene Transfer, Virulence Factors, and Future Perspectives.Frontiers in cellular and infection microbiology · 2022Review
- The Role of Thoracic Ultrasonography and Airway Endoscopy in the Diagnosis of Equine Asthma and Exercise-Induced Pulmonary Hemorrhage.Veterinary sciences · 2021Article
- Nicoletella semolina in the airways of healthy horses and horses with severe asthma.Journal of veterinary internal medicine · 2021Article
- Characterization of the seminal bacterial microbiome of healthy, fertile stallions using next-generation sequencing.Animal reproduction · 2021Article
- Nasopharyngeal Microbiomes in Donkeys SheddingFrontiers in veterinary science · 2021Article
- Tracheal microbial populations in horses with moderate asthma.Journal of veterinary internal medicine · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are limited data on potential dysbiosis of the airway microbiota in horses with asthma. HYPOTHESIS/
objectivesWe hypothesized that the respiratory microbiota of horses with moderate asthma is altered. Our objectives were (a) to quantify tracheal bacterial populations using culture and qPCR, (2) to compare aerobic culture and qPCR, and (c) to correlate bacterial populations with bronchoalveolar lavage fluid (BALF) cytology. ANIMALS: Eighteen horses with moderate asthma from a hospital population and 10 controls.
methodsProspective case-control study. Aerobic culture was performed on tracheal aspirates, and streptococci, Pasteurella multocida, Chlamydophila spp., Mycoplasma spp., as well as 16S (bacterial) and 18S (fungal) rRNA subunits were quantified by qPCR.
resultsPotential pathogens such as Streptococcus spp., Actinobacillus spp., and Pasteurellaceae were isolated from 8, 5, and 6 horses with asthma and 3, 0, and 2 controls, respectively. There was a positive correlation between Streptococcus spp. DNA and 16S rRNA gene (r ≥ 0.7, P ≤ 0.02 in both groups), but the overall bacterial load (16S) was lower in asthma (1.5 ± 1.3 versus 2.5 ± 0.8 × 10 CONCLUSIONS AND CLINICAL IMPORTANCE: This study does not support that bacterial overgrowth is a common feature of chronic moderate asthma in horses. Lower bacterial load could suggest dysbiosis of the lower airways, either as a consequence of chronic inflammation or previous treatments, or as a perpetuating factor of inflammation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.