ArticleThe EMBO journal2020
α-Actinin-1 promotes activity of the L-type Ca
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- NMDA Receptor Regulation by Calmodulin and α-Actinin-1.Biomolecules · 2026Review
- Structural Insights into L-Type Voltage-Gated CaBiochemistry · 2026Article
- 2-MCPD-Induced Effects in the Heart: Toxicological and Mechanistic Implications from Comparative Proteomic Analyses in Rats.Molecules (Basel, Switzerland) · 2026Article
- α-Actinin-1 in Megakaryocytes: Its Structure, Interacting Proteins and Implications for Thrombopoiesis.Biomedicines · 2025Review
- L-Type Voltage-Gated CaBiochemistry · 2025Article
- Structural biology of voltage-gated calcium channels.Channels (Austin, Tex.) · 2024Review
- Chemical shift assignments of the α-actinin C-terminal EF-hand domain bound to a cytosolic C0 domain of GluN1 (residues 841-865) from the NMDA receptor.Biomolecular NMR assignments · 2024Article
- CaCommunications biology · 2024Article
- ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.Journal of experimental & clinical cancer research : CR · 2023Article
- αeLife · 2023Article
- 4'‑O‑methylbavachalcone inhibits succinate induced cardiomyocyte hypertrophy via the NFATc4 pathway.Experimental and therapeutic medicine · 2023Article
- Regulation of Cardiac Cav1.2 Channels by Calmodulin.International journal of molecular sciences · 2023Review
- Calmodulin promotes a CaFEBS letters · 2022Article
- Chemical shift assignments of calmodulin under standard conditions at neutral pH.Biomolecular NMR assignments · 2022Article
- Chemical shift assignments of calmodulin bound to the β-subunit of a retinal cyclic nucleotide-gated channel (CNGB1).Biomolecular NMR assignments · 2022Article
- L-Type CaBiomolecules · 2021Review
- EVAP: A two-photon imaging tool to study conformational changes in endogenous Kv2 channels in live tissues.The Journal of general physiology · 2021Article
- Ciliary GPCR-based transcriptome as a key regulator of cilia length control.FASEB bioAdvances · 2021Article
- The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site.Biochemistry · 2021Article
- Tissue-specific adrenergic regulation of the L-type CaScience signaling · 2020Review
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 1 institution in 1 country.
Matthew Turner *Department of Chemistry, University of California, Davis, CA, USA.
David E Anderson *Department of Chemistry, University of California, Davis, CA, USA.
Peter Bartels *Department of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0001-5852-1835
Madeline Nieves-Cintron *Department of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0003-1935-8400
Andrea M ColemanDepartment of Chemistry, University of California, Davis, CA, USA.ORCID 0000-0001-7564-8723
Peter B HendersonDepartment of Pharmacology, University of California, Davis, CA, USA.
Kwun Nok Mimi ManDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0002-0132-9129
Pang-Yen TsengDepartment of Pharmacology, University of California, Davis, CA, USA.
Vladimir Yarov-YarovoyDepartment of Physiology and Membrane Biology, University of California, Davis, CA, USA.ORCID 0000-0002-2325-4834
Donald M BersDepartment of Pharmacology, University of California, Davis, CA, USA.
Manuel F NavedoDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0001-6864-6594
Mary C HorneDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0002-2799-3212
James B AmesDepartment of Chemistry, University of California, Davis, CA, USA.ORCID 0000-0003-0934-2595
Johannes W HellDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0001-7960-7531
University of California, Davis · US
Funding
MEMBRANE TARGETING CALCIUM SENSORS IN VISIONR01EY012347 · NEI · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI AMES, JAMES B · 1999 to 2023
$6.9MCoupling of Vascular Cav1.2 Channels In Health & DiseaseR01HL121059 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2015 to 2024
$4.5MRole of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0MCalcium Sparklets-Induced Vascular Dysfunction During DiabetesR01HL098200 · NHLBI · UNIVERSITY OF WASHINGTON · PI NAVEDO, MANUEL F · 2010 to 2019
$3.5MSubcellular Localization of Cav1.2 by alpha-actininR01AG017502 · NIA · UNIVERSITY OF WISCONSIN MADISON · PI HELL, JOHANNES W · 2000 to 2011
$3.3MMolecular Mechanisms of Postsynaptic AMPA Receptor LocalizationR01MH097887 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2014 to 2018
$2.5MPredoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2MSignaling by cAMP within postsynaptic nano domains R01NS078792R01NS078792 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2016
$2.0MUC Davis Training Program in Chemical BiologyT32GM113770 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BEAL, PETER A. · 2015 to 2019
$742kAmerican Heart Association (AHA) 14PRE19900021NEI NIH HHS R01 EY012347NHLBI NIH HHS R01 HL098200NHLBI NIH HHS R01 HL121059NIA NIH HHS R01 AG017502NIA NIH HHS R01 AG055357NIGMS NIH HHS T32 GM099608NIGMS NIH HHS T32 GM113770NIMH NIH HHS R01 MH097887NINDS NIH HHS R01 NS078792
Abstract
The L-type Ca
Indexed as
ActininAmino Acid SubstitutionCalciumCalcium Channels, L-TypeCalmodulinHumansMutationNeuronsProtein BindingActininACTN1 protein, humanCalciumCalcium Channels, L-TypeCalmodulincalmodulingating chargeIQ motif structureopen probabilitysurface expression
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.