Evidence map›Paper›PMID 31984809›Full record

ArticleDrug delivery2020

Synthesis of novel, DNA binding heterocyclic dehydroabietylamine derivatives as potential antiproliferative and apoptosis-inducing agents.

Fengyi Zhao, Xu Sun, Wen Lu, Li Xu, Jiuzhou Shi, Shilong Yang, Mengyi Zhou, Fan Su, Feng Lin, Fuliang Cao

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Research on Anthocyanins fromFoods (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fengyi ZhaoCo-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, PR China.
Xu SunCollege of Science, Nanjing Forestry University, Nanjing, PR China.
Wen LuCollege of Science, Nanjing Forestry University, Nanjing, PR China.
Li XuCo-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, PR China.
Jiuzhou ShiCollege of Science, Nanjing Forestry University, Nanjing, PR China.
Shilong YangAdvanced Analysis and Testing Center, Nanjing Forestry University, Nanjing, PR China.
Mengyi ZhouAdvanced Analysis and Testing Center, Nanjing Forestry University, Nanjing, PR China.
Fan SuAdvanced Analysis and Testing Center, Nanjing Forestry University, Nanjing, PR China.
Feng LinAdvanced Analysis and Testing Center, Nanjing Forestry University, Nanjing, PR China.
Fuliang CaoCo-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, PR China.
Nanjing Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several dehydroabietylamine derivatives containing heterocyclic moieties such as thiophene and pyrazine ring were successfully synthesized. The antiproliferative activities of these thiophene-based Schiff-bases, thiophene amides, and pyrazine amides were investigated

Indexed as

AbietanesApoptosisCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDoxycyclineHumansInhibitory Concentration 50Molecular StructureAbietanesdehydroabietylamineDoxycyclineantiproliferativeapoptosisDehydroabietylamine derivativeslower toxicity

Identifiers

PMID31984809
PMCPMC7034089
OpenAlexW3003134774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.