Evidence map›Paper›PMID 31984733›Full record

ArticleJournal of agricultural and food chemistry2020

"Bottom-Up" Strategy for the Identification of Novel Soybean Peptides with Angiotensin-Converting Enzyme Inhibitory Activity.

Luca Dellafiora, Raffaele Pugliese, Carlotta Bollati, Fabrizio Gelain, Gianni Galaverna, Anna Arnoldi, Carmen Lammi

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luca DellafioraDepartment of Food and Drug , University of Parma , Parma 43124 , Italy.ORCID http://orcid.org/0000-0002-1901-3317
Raffaele PuglieseTissue Engineering Unit , Institute for Stem Cell Biology, Regenerative Medicine and Innovative Therapies-ISBReMIT, Fondazione IRCSS Casa Sollievo della Sofferenza , San Giovanni Rotondo 71013 , Foggia , Italy.ORCID http://orcid.org/0000-0001-7669-4457
Carlotta BollatiDepartment of Pharmaceutical Sciences , University of Milan , Milan 20133 , Italy.
Fabrizio GelainTissue Engineering Unit , Institute for Stem Cell Biology, Regenerative Medicine and Innovative Therapies-ISBReMIT, Fondazione IRCSS Casa Sollievo della Sofferenza , San Giovanni Rotondo 71013 , Foggia , Italy.
Gianni GalavernaDepartment of Food and Drug , University of Parma , Parma 43124 , Italy.
Anna ArnoldiDepartment of Pharmaceutical Sciences , University of Milan , Milan 20133 , Italy.ORCID http://orcid.org/0000-0002-0987-3014
Carmen LammiDepartment of Pharmaceutical Sciences , University of Milan , Milan 20133 , Italy.ORCID http://orcid.org/0000-0002-7428-4486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IAVPTGVA (Soy1) and LPYP are two soybean peptides, which display a multifunctional behavior, showing in vitro hypocholesterolemic and hypoglycemic activities. A preliminary screening of their structures using BIOPEP suggested that they might be potential angiotensin-converting enzyme (ACE) inhibitors. Therefore, a bottom-up-aided approach was developed in order to clarify the in vitro hypotensive activity. Soy1 and LPYP dropped the intestinal and renal ACE enzyme activity with IC

Indexed as

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCell LineCell SurvivalGlycine maxHumansPeptidesPeptidyl-Dipeptidase APlant ExtractsSpectroscopy, Fourier Transform InfraredAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsPeptidesPeptidyl-Dipeptidase APlant ExtractsACEbioactive peptideshypotensive peptidesmultifunctional peptidespeptide encapsulationself-assembling peptides

Identifiers

PMID31984733
PMCPMC7997397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.