Evidence map›Paper›PMID 31984673›Full record

ArticleChemSusChem2020

Assessing the Viability of Recovery of Hydroxycinnamic Acids from Lignocellulosic Biorefinery Alkaline Pretreatment Waste Streams.

Steven D Karlen, Peyman Fasahati, Mona Mazaheri, Jose Serate, Rebecca A Smith, Sirisha Sirobhushanam, Mingjie Chen, Vitaliy I Tymokhin, Cynthia L Cass, Sarah Liu and 13 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemSusChem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
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  4. A distinct subpopulation of membrane vesicles inApplied and environmental microbiology · 2025
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  10. Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1.Biotechnology for biofuels and bioproducts · 2024
    Article
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  12. Article
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  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Steven D KarlenDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-2044-8895
Peyman FasahatiDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0003-0910-1695
Mona MazaheriDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Jose SerateDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Rebecca A SmithDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0003-2363-2820
Sirisha SirobhushanamDOE Great Lakes Bioenergy Research Center, School of Biological Sciences, Illinois State University, Normal, IL, 61790, USA.
Mingjie ChenDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-7400-5192
Vitaliy I TymokhinDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-6978-1242
Cynthia L CassDOE Great Lakes Bioenergy Research Center, School of Biological Sciences, Illinois State University, Normal, IL, 61790, USA.
Sarah LiuDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Dharshana PadmakshanDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Dan XieDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Yaoping ZhangDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-6887-8982
Mick A McGeeDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0001-9178-2703
Jason D RussellDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Joshua J CoonDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-0004-8253
Heidi F KaepplerDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Natalia de LeonDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0001-7867-9058
Christos T MaraveliasDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
Troy M RungeDepartment of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Shawn M KaepplerDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0002-5964-1668
John C SedbrookDOE Great Lakes Bioenergy Research Center, School of Biological Sciences, Illinois State University, Normal, IL, 61790, USA.ORCID http://orcid.org/0000-0002-4930-1627
John RalphDOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, 53726, USA.
University of Wisconsin–Madison · USGreat Lakes Bioenergy Research Center · US

Funding

Office of Science DE-FC02-07ER64494Office of Science DE-SC0018409
6 · The paper itself

Abstract

The hydroxycinnamic acids p-coumaric acid (pCA) and ferulic acid (FA) add diversity to the portfolio of products produced by using grass-fed lignocellulosic biorefineries. The level of lignin-bound pCA in Zea mays was modified by the alteration of p-coumaroyl-CoA monolignol transferase expression. The biomass was processed in a lab-scale alkaline-pretreatment biorefinery process and the data were used for a baseline technoeconomic analysis to determine where to direct future research efforts to couple plant design to biomass utilization processes. It is concluded that future plant engineering efforts should focus on strategies that ramp up accumulation of one type of hydroxycinnamate (pCA or FA) predominantly and suppress that of the other. Technoeconomic analysis indicates that target extraction titers of one hydroxycinnamic acid need to be >50 g kg

Indexed as

acidsbiomassindustrial chemistryprotein engineeringsynthesis design

Identifiers

PMID31984673
PMCPMC7217007
OpenAlexW3001513691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.