Evidence map›Paper›PMID 31984498›Full record

ArticleMedical physics2020

Multi-energy inter-pixel coincidence counters for charge sharing correction and compensation in photon counting detectors.

Katsuyuki Taguchi

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  7. Number of energy windows for photon counting detectors: is more actually more?Journal of medical imaging (Bellingham, Wash.) · 2024
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  8. Article
  9. [A comprehensive review on photon-counting computed tomography: Principles, technical hurdles and analysis of clinical applications].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
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  13. Spectral Photon Counting CT: Imaging Algorithms and Performance Assessment.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Katsuyuki TaguchiRadiological Physics Division, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 4253, Baltimore, MD, 21287, USA.
Johns Hopkins Medicine · US

Funding

Quasi-ideal photon counting x-ray CT with multi-energy inter-pixel coincidence counter (MEICC)R21EB029739 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI TAGUCHI, KATSUYUKI · 2020 to 2021
$436k
NIBIB NIH HHS R21 EB029739
6 · The paper itself

Abstract

purposeSmaller pixel sizes of x-ray photon counting detectors (PCDs) are advantageous for count rate capabilities but disadvantageous for charge sharing. With charge sharing, the energy of an x-ray photon may be split and one photon may produce two or more counts at adjacent pixels, both at lower energies than the incident energy. This "double-counting" increases noise variance and degrades the spectral response. Overall, it has a significantly negative impact on the performance of PCD-based computed tomography (CT). Charge sharing is induced by the detection physics and occurs regardless of count rates; thus, it is impossible to avoid. We propose in this paper a method that has a potential to address both noise and bias added by charge sharing.

methodsWe propose applying a multi-energy inter-pixel coincidence counter (MEICC) technique, which uses energy-dependent coincidence counters, keeps the book of charge sharing events during data acquisition, and provides the exact number of charge sharing occurrences, which can be used to either correct or compensate for them after the acquisition is completed. MEICC does not interfere with the primary counting process; therefore, PCDs with MEICC will remain as fast as those without MEICC. MEICC can be implemented using current electronics technology because its inter-pixel coincidence counters used to handle digital data are rather simple. We evaluated Cramér-Rao lower bound (CRLB) of PCDs with and without MEICC using a Monte Carlo simulation.

resultsWhen the number of energy windows was four or larger and eight neighboring pixels were used, the CRLBs of 225-µm PCD with MEICC normalized by those of the current PCD with the same number of windows were 0.361-0.383 for water density images of two basis functions, which was only 5.7-16.4% worse than those of a PCD without charge sharing (which were at 0.329-0.358). In contrast, the normalized CRLBs of the PCD with one coincidence counter were 0.466-0.499, which were 37.3-45.6% worse than the PCD without charge sharing. The use of eight neighboring pixels provided ~10% better CRLB values than four neighboring pixels for MEICC. With four energy windows, decreasing the number of coincidence counters from 16 to 9 only slightly increased the CRLB from 0.255 to 0.269 (which corresponded to as little as a 5.5% change). The normalized CRLBs of MEICC for K-edge imaging (gold) were 0.295-0.426, while those of the one coincidence counter were 0.926-0.959 and the ideal PCDs were 0.126-0.146.

conclusionsThe proposed MEICC provides spectral information that can be used to address charge sharing problems in PCDs and is expected to satisfy the requirements for clinical x-ray CT. MEICC is very effective, especially for K-edge imaging, which requires accurate spectral information.

Indexed as

PhotonsCalibrationScintillation Countingcharge sharingcomputed tomographyphoton countingspectral response

Identifiers

PMID31984498
PMCPMC10029749
OpenAlexW3001143044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.