Evidence map›Paper›PMID 31984429›Full record

ReviewNano convergence2020

High density lipoprotein mimicking nanoparticles for atherosclerosis.

Jun Chen, Xixi Zhang, Reid Millican, Jacob Emil Creutzmann, Sean Martin, Ho-Wook Jun

Open access · diamondAbstract readReview
In one paragraph

Review in Nano convergence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Recent Advances in Nanozymes for the Treatment of Atherosclerosis.International journal of nanomedicine · 2025
    Review
  9. Review
  10. Nano Delivery System for Atherosclerosis.Journal of functional biomaterials · 2024
    Review
  11. Article
  12. Review
  13. Advances in Atherosclerosis Theranostics Harnessing Iron Oxide-Based Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  14. Photodynamic Therapy for Atherosclerosis.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Expression of recombinant human Apolipoprotein A-IBioresources and bioprocessing · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jun ChenDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Xixi ZhangDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Reid MillicanDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Jacob Emil CreutzmannDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Sean MartinDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Ho-Wook JunDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA. hwjun@uab.edu.ORCID http://orcid.org/0000-0001-9150-7189
University of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Prohealing multifunctional endothelium nanomatrix coated stentR01HL125391 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JUN, HO-WOOK · 2015 to 2019
$1.8M
American Heart Association 18POST34080260NHLBI NIH HHS 1R01HL125391NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Atherosclerosis is a major contributor to many cardiovascular events, including myocardial infarction, ischemic stroke, and peripheral arterial disease, making it the leading cause of death worldwide. High-density lipoproteins (HDL), also known as "good cholesterol", have been shown to demonstrate anti-atherosclerotic efficacy through the removal of cholesterol from foam cells in atherosclerotic plaques. Because of the excellent anti-atherosclerotic properties of HDL, in the past several years, there has been tremendous attention in designing HDL mimicking nanoparticles (NPs) of varying functions to image, target, and treat atherosclerosis. In this review, we are summarizing the recent progress in the development of HDL mimicking NPs and their applications for atherosclerosis.

Indexed as

AtherosclerosisHigh-density lipoproteinImaging contrast agentsNanoparticlesTheranostic agentsTherapeutic delivery

Identifiers

PMID31984429
PMCPMC6983461
OpenAlexW3004959064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.