Evidence map›Paper›PMID 31984369›Full record

ArticleJAMIA open2019

A tale of three subspecialties: Diagnosis recording patterns are internally consistent but Specialty-Dependent.

Jose-Franck Diaz-Garelli, Roy Strowd, Tamjeed Ahmed, Brian J Wells, Rebecca Merrill, Javier Laurini, Boris Pasche, Umit Topaloglu

Abstract read
In one paragraph

Article in JAMIA open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Electronic health record data quality assessment and tools: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2023
    Pooled it
  2. Digital Health Data Quality Issues: Systematic Review.Journal of medical Internet research · 2023
    Pooled it
  3. Review
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  8. Building Cancer Diagnosis Text to OncoTree Mapping Pipelines for Clinical Sequencing Data Integration and Curation.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  9. Article
  10. Exploring the Hazards of Scaling Up Clinical Data Analyses: A Drug Side Effect Discovery Case Report.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jose-Franck Diaz-GarelliWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.ORCID 0000-0002-4346-3799
Roy StrowdWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Tamjeed AhmedWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Brian J WellsWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Rebecca MerrillWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Javier LauriniWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Boris PascheWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.
Umit TopalogluWake Forest Baptist Medical Center, Winston Salem, North Carolina, USA.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Postdoctoral Research, Instruction, and Mentoring Experience (PRIME)K12GM102773 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOWLETT, ALLYN C · 2013 to 2018
$2.6M
NCATS NIH HHS UL1 TR001420NIGMS NIH HHS K12 GM102773
6 · The paper itself

Abstract

backgroundStructured diagnosis (DX) are crucial for secondary use of electronic health record (EHR) data. However, they are often suboptimally recorded. Our previous work showed initial evidence of variable DX recording patterns in oncology charts even after biopsy records are available.

objectiveWe verified this finding's internal and external validity. We hypothesized that this recording pattern would be preserved in a larger cohort of patients for the same disease. We also hypothesized that this effect would vary across subspecialties.

methodsWe extracted DX data from EHRs of patients treated for brain, lung, and pancreatic neoplasms, identified through clinician-led chart reviews. We used statistical methods (i.e., binomial and mixed model regressions) to test our hypotheses.

resultsWe found variable recording patterns in brain neoplasm DX (i.e., larger number of distinct DX-OR = 2.2,

conclusionOur results suggest that disease-specific DX entry patterns exist and are established differently by clinical subspecialty. These differences should be accounted for during clinical data reuse and data quality assessments but also during EHR entry system design to maximize accurate, precise and consistent data entry likelihood.

Indexed as

clinical data managementdata qualityelectronic health recordslearning healthcare systemsecondary use of clinical data

Identifiers

PMID31984369
PMCPMC6951969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.