Evidence map›Paper›PMID 31984241›Full record

ArticleWellcome open research2019

Polygenic risk score for Alzheimer's disease and trajectories of cardiometabolic risk factors in children.

Roxanna Korologou-Linden, Linda O'Keeffe, Laura D Howe, George Davey-Smith, Hannah J Jones, Emma L Anderson, Evie Stergiakouli

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Roxanna Korologou-LindenMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Linda O'KeeffeMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Laura D HoweMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0003-3357-2796
George Davey-SmithMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-1407-8314
Hannah J JonesMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-5883-9605
Emma L AndersonMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Evie StergiakouliMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0003-3586-0927
University Of Bristol Dental Hospital · GB

Funding

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
NATIONAL ALZHEIMERS COORDINATING CENTER (NACC)U01AG016976 · NIA · UNIVERSITY OF WASHINGTON · PI KUKULL, WALTER ANTHONY · 1999 to 2020
$72.8M
Alzheimer's Disease Genetics ConsortiumU01AG032984 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SCHELLENBERG, GERARD DAVID · 2009 to 2024
$60.4M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Collaborative GWAS of Dementia, AD and related MRI and Cognitive EndophenotypesR01AG033193 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SESHADRI, SUDHA · 2009 to 2016
$4.4M
Physical activity and childhood obesityR01HL071248 · NHLBI · UNIVERSITY OF BRISTOL · PI COOPER, ASHLEY RONALD · 2003 to 2010
$4.0M
Maternal overnutrition and offspring fat mass, metabolic and vascular function.R01DK077659 · NIDDK · UNIVERSITY OF BRISTOL · PI LAWLOR, DEBORAH ANNE · 2006 to 2009
$986k
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MR/P014437/1NHLBI NIH HHS R01 HL071248NHLBI NIH HHS R01 HL105756NIA NIH HHS R01 AG033193NIA NIH HHS U01 AG016976NIA NIH HHS U01 AG032984NIA NIH HHS U24 AG021886NIDDK NIH HHS R01 DK077659Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer's diseasecardiometabolicpolygenic risk scorestrajectories

Identifiers

PMID31984241
PMCPMC6971849
OpenAlexW2969235561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.