ArticleCase reports in rheumatology2020
Ankylosing Spondyloarthritis Resulting Severe Aortic Insufficiency and Aortitis: Exacerbation of Ankylosing Spondyloarthritis and Stenosis of the Main Left Coronary Artery after Mechanical Aortic Valve Implantation with Cardiopulmonary Bypass.
Article in Case reports in rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Multi-omics analysis of genetic drivers linking aortic stenosis and left ventricular diastolic dysfunction in heart failure.BioData mining · 2026Article
- Article
- A case of ankylosing spondylitis presenting with fever of unknown origin diagnosed as aortitis: A case report.Clinical case reports · 2023Article
- The relationship of serum visfatin levels with clinical parameters, flow-mediated dilation, and carotid intima-media thickness in patients with ankylosing spondylitisTurkish journal of medical sciences · 2021Article
- Heart Involvement in a Moroccan Population with Spondyloarthritis: A Cross-sectional Study.Journal of the Saudi Heart Association · 2021Article
- Transcatheter Aortic Valve Replacement in a Patient with Ankylosing Spondylitis and Complex Valvulopathy: Managing Aortic Regurgitation, Mitral Regurgitation, and Ventricular Arrhythmias.Journal of cardiovascular echographyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
Ankylosing spondyloarthritis (AS) is a chronic inflammatory rheumatic disease, strongly related to human leukocyte antigen (HLA)-B27. Cardiac involvement in AS manifests in 2 to 10% of patients as aortic insufficiency, aortitis, mitral valve fibrosis, or disturbance in the conduction of the heart. In this article, we present a case of a 49-year-old male patient with AS, who was referred to our medical institution for elective aortic valve surgery because of severe aortic regurgitation. The histological findings revealed fibrosing endocarditis of aortic valve and nonspecific aortitis of aortic root. Late postoperatively, we observed exacerbation of AS and narrowing of the main left coronary artery (LAD). Our case highlights the importance of proper treatment of AS before and after cardiac surgery. Furthermore, in this case, we suspect association between cardiopulmonary bypass, activity of AS, and coronary artery disease.
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Registered trials
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