Evidence map›Paper›PMID 31984125›Full record

ReviewWorld journal of cardiology2020

Radial artery access site complications during cardiac procedures, clinical implications and potential solutions: The role of nitric oxide.

Emma M Coghill, Timothy Johnson, Russell E Morris, Ian L Megson, Stephen J Leslie

Abstract readReview
In one paragraph

Review in World journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. La Tunisie medicale · 2023
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Radial artery access in interventional cardiology: a review of current practices.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emma M CoghillFree Radical Research Facility, Division of Biomedical Sciences, University of the Highlands and Islands, Inverness IV2 3JH, United Kingdom.
Timothy JohnsonJohnson Matthey Technology Centre, Blount's Court, Sonning Common, Reading RG4 9NH, United Kingdom.
Russell E MorrisSchool of Chemistry, University of St. Andrews, St Andrews KY16 9ST, United Kingdom.
Ian L MegsonFree Radical Research Facility, Division of Biomedical Sciences, University of the Highlands and Islands, Inverness IV2 3JH, United Kingdom.
Stephen J LeslieDepartment of Cardiology, NHS Highland, Inverness IV2 3UJ, United Kingdom. stephen.leslie@nhs.net.

Funding

British Heart Foundation NH/11/8/29253
6 · The paper itself

Abstract

Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery, as this is safer than the femoral approach. However, despite improvements in technology and techniques, complications can occur. The most common complication, arterial spasm, can cause intense pain and, in some cases, procedural failure. The incidence of spasm is dependent on several variables, including operator experience, artery size, and equipment used. An anti-spasmolytic cocktail can be applied to reduce spasm, which usually includes an exogenous nitric oxide (NO) donor (glyceryl trinitrate). NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm intervention. However, systemic administration can result in unwanted side-effects, such as hypotension. A method that adopts local delivery of NO might be advantageous. This review article describes the mechanisms involved in radial artery spasm, discusses the advantages and disadvantages of current strategies to reduce spasm, and highlight the potential of NO-loaded nanoporous materials for use in this setting.

Indexed as

CannulationNanoporous materialNitric oxideRadial arterySpasmVasodilation

Identifiers

PMID31984125
PMCPMC6952722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.