Evidence map›Paper›PMID 31983324›Full record

ArticleJournal of the American Heart Association2020

Is Carotid Intima-Media Thickness Increased in Adults With Congenital Heart Disease?

Barbara Reiner, Renate Oberhoffer, Anna-Luisa Häcker, Peter Ewert, Jan Müller

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Barbara ReinerDepartment of Paediatric Cardiology and Congenital Heart Disease German Heart Centre Munich Technical University Munich Munich Germany.
Renate OberhofferDepartment of Paediatric Cardiology and Congenital Heart Disease German Heart Centre Munich Technical University Munich Munich Germany.
Anna-Luisa HäckerDepartment of Paediatric Cardiology and Congenital Heart Disease German Heart Centre Munich Technical University Munich Munich Germany.
Peter EwertDepartment of Paediatric Cardiology and Congenital Heart Disease German Heart Centre Munich Technical University Munich Munich Germany.
Jan MüllerDepartment of Paediatric Cardiology and Congenital Heart Disease German Heart Centre Munich Technical University Munich Munich Germany.
Deutsches Herzzentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Because of the increasing numbers of congenital patients surviving into adulthood, early diagnosis and prevention of acquired cardiovascular disease is reasonable. The aim of this study was to detect diagnostic subgroups of adults with congenital heart disease (ACHD) that have increased carotid intima-media thickness (cIMT), a subclinical marker of cardiovascular damage. Methods and Results This study enrolled 831 ACHD patients (392 women, aged 38.8±11.7 years) from May 2015 to February 2019 at their regular outpatient visit. Far wall cIMT was measured using a semiautomatic ultrasound system at 4 angles. Age, sex, height, weight, blood pressure, smoking status, and antihypertensive medication were registered and entered in a multiple linear regression model to compare diagnostic subgroups to 191 healthy controls (111 women, aged 36.7±13.5 years). There were no significant differences in cIMT of ACHD (0.538±0.086 mm) compared with healthy controls (0.541±0.083 mm;

Indexed as

Carotid Intima-Media ThicknessAdolescentAdultAgedAged, 80 and overAortic CoarctationCarotid Artery DiseasesCase-Control StudiesFemaleGermanyHeart Defects, CongenitalHumansMaleMiddle AgedPredictive Value of TestsPrevalenceadults with congenital heart diseasecarotid intima‐media thicknesscoarctation of the aorta

Identifiers

PMID31983324
PMCPMC7033861
OpenAlexW3002916147

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.