Evidence map›Paper›PMID 31983258›Full record

ReviewDrug delivery2020

Self-Assembled chitosan/phospholipid nanoparticles: from fundamentals to preparation for advanced drug delivery.

Qingming Ma, Yang Gao, Wentao Sun, Jie Cao, Yan Liang, Shangcong Han, Xinyu Wang, Yong Sun

Abstract readReview
In one paragraph

Review in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. New Acaciin-Loaded Self-Assembled Nanofibers as MInternational journal of nanomedicine · 2021
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qingming MaDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Yang GaoDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Wentao SunCenter for Basic Medical Research, TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Jie CaoDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Yan LiangDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.ORCID http://orcid.org/0000-0003-1084-6117
Shangcong HanDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Xinyu WangInstitute of Thermal Science and Technology, Shandong University, Jinan, China.
Yong SunDepartment of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of nanotechnology, self-assembled chitosan/phospholipid nanoparticles (SACPNs) show great promise in a broad range of applications, including therapy, diagnosis, in suit imaging and on-demand drug delivery. Here, a brief review of the SACPNs is presented, and its critical underlying formation mechanisms are interpreted with an emphasis on the intrinsic physicochemical properties. The state-of-art preparation methods of SACPNs are summarized, with particular descriptions about the classic solvent injection method. Then SACPNs microstructures are characterized, revealing the unique spherical core-shell structure and the drug release mechanisms. Afterwards, a comprehensive and in-depth depiction of their emerging applications, with special attention to drug delivery areas, are categorized and reviewed. Finally, conclusions and outlooks on further advancing the SACPNs toward a more powerful and versatile platform for investigations covering from fundamental understanding to developing multi-functional drug delivery systems are discussed.

Indexed as

Chemistry, PharmaceuticalChitosanDrug CarriersDrug LiberationHydrogen-Ion ConcentrationNanoparticlesParticle SizePhospholipidsChitosanDrug CarriersPhospholipidschitosandrug deliverynanoparticlesphospholipidsSelf-assembly

Identifiers

PMID31983258
PMCPMC7034086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.