Evidence map›Paper›PMID 31983241›Full record

ArticleThe American journal of drug and alcohol abuse2020

Effect of witnessing an overdose on the use of drug checking services among people who use illicit drugs in Vancouver, Canada.

Tara Beaulieu, Kanna Hayashi, Ekaterina Nosova, M-J Milloy, Kora DeBeck, Evan Wood, Thomas Kerr, Lianping Ti

Open access · greenAbstract read
In one paragraph

Article in The American journal of drug and alcohol abuse, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tara Beaulieu, British Columbia Centre on Substance Use , Vancouver, BC, Canada.
Kanna Hayashi, British Columbia Centre on Substance Use , Vancouver, BC, Canada.ORCID 0000-0003-3843-2928
Ekaterina Nosova, British Columbia Centre on Substance Use , Vancouver, BC, Canada.
M-J Milloy, British Columbia Centre on Substance Use , Vancouver, BC, Canada.
Kora DeBeck, British Columbia Centre on Substance Use , Vancouver, BC, Canada.
Evan Wood, British Columbia Centre on Substance Use , Vancouver, BC, Canada.ORCID 0000-0001-9412-6699
Thomas Kerr, British Columbia Centre on Substance Use , Vancouver, BC, Canada.ORCID 0000-0002-0870-7153
Lianping Ti, British Columbia Centre on Substance Use , Vancouver, BC, Canada.
University of British Columbia · CASimon Fraser University · CABritish Columbia Centre on Substance Use · CA

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersR01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2007 to 2016
$5.8M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
NIDA NIH HHS R01 DA021525NIDA NIH HHS U01 DA021525NIDA NIH HHS U01 DA038886
6 · The paper itself

Abstract

backgroundSince 2013, fentanyl-contaminated drugs have been driving North America's opioid-overdose epidemic. Drug checking, which enables people who use illicit drugs (PWUD) to test and receive feedback regarding the contents of their drugs, is being considered as a potential tool to address the toxic drug supply. While some PWUD witness overdoses, little is known about the impact of these experiences on subsequent risk reduction practices.

objectiveThe purpose of this study was to examine the effect of witnessing an overdose on drug checking service use.

methodsData were derived from prospective cohorts of PWUD in Vancouver, Canada, a setting with a community-wide fentanyl overdose crisis, between June 1, 2018 and December 1, 2018. Multivariable logistic regression was used to estimate the effect of witnessing an overdose on drug checking service use.

results1,426 participants were eligible for the study, including 530 females; 767 (53.8%) participants reported witnessing an overdose and 196 (13.7%) reported using drug checking services in the last 6 months. In multivariable analyses, after adjusting for a range of confounders including the use of fentanyl, witnessing an overdose was positively associated with drug checking service use (adjusted odds ratio = 2.32; 95% confidence interval: 1.57-3.49).

conclusionOur findings suggest that witnessing an overdose may motivate PWUD to use drug checking services. Given that only a small proportion of PWUD in the study reported using drug checking services, our findings highlight the need to continue to scale-up a range of overdose prevention interventions.

Indexed as

AdultAnalgesics, OpioidCanadaDrug ContaminationDrug OverdoseDrug UsersFemaleFentanylHarm ReductionHumansIllicit DrugsMaleMiddle AgedProspective StudiesSubstance-Related DisordersAnalgesics, OpioidFentanylIllicit Drugsdrug checkingfentanylillicit drugsopioidsOverdoseVancouver

Identifiers

PMID31983241
PMCPMC7382612
OpenAlexW3001665964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.