Evidence map›Paper›PMID 31982997›Full record

ArticleEnvironmental science and pollution research international2020

In vivo and in vitro analysis of cytogenotoxicity in populations living in abnormal conditions from Santos-Sao Vicente estuary.

Maria Esther Suarez Alpire, Elaine Aparecida de Camargo, Caroline Margonato Cardoso, Daisy Maria Favero Salvadori, Camilo Dias Seabra Pereira, Daniel Araki Ribeiro

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria Esther Suarez AlpireDepartamento de Biociências, Universidade Federal de São Paulo, UNIFESP, Av. Ana Costa, 95, Vila Mathias, Santos, SP, 11060-001, Brazil.
Elaine Aparecida de CamargoDepartment of Pathology, Botucatu Medical School, São Paulo State University, UNESP, Botucatu, SP, Brazil.
Caroline Margonato CardosoDepartamento de Biociências, Universidade Federal de São Paulo, UNIFESP, Av. Ana Costa, 95, Vila Mathias, Santos, SP, 11060-001, Brazil.
Daisy Maria Favero SalvadoriDepartment of Pathology, Botucatu Medical School, São Paulo State University, UNESP, Botucatu, SP, Brazil.
Camilo Dias Seabra PereiraDepartment of Sea Sciences, Federal University of São Paulo, UNIFESP, Campus Baixada Santista, Santos, SP, Brazil.
Daniel Araki RibeiroDepartamento de Biociências, Universidade Federal de São Paulo, UNIFESP, Av. Ana Costa, 95, Vila Mathias, Santos, SP, 11060-001, Brazil. daribeiro@unifesp.br.ORCID http://orcid.org/0000-0001-5057-4983
Universidade Federal de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

cnpQ 001
6 · The paper itself

Abstract

The aim of the study was to evaluate cyto- and genotoxic effects in populations living in subnormal clusters in Santos São Vicente estuary. For in vivo study, samples of buccal mucosa and peripheral blood cells were collected. Micronucleus assay and single-cell gel (comet) assay were performed. For in vitro study, Chinese ovary hamster (CHO) cells were exposed to contaminated water. The results showed that people living in the contaminated estuary have increased DNA damage in oral mucosa and peripheral blood cells, as detected in the micronucleus and comet assays respectively. In addition, estuarine water was able to promote cytotoxicity at the highest concentrations, as well as decrease the number of cells in the G1 phase. In summary, our results indicate that water from the Santos-São Vicente estuary is capable of inducing cytogenotoxicity in mammalian cells in vivo and in vitro.

Indexed as

EstuariesAnimalsComet AssayCricetinaeDNA DamageMicronucleus TestsWaterWater Pollutants, ChemicalWaterWater Pollutants, ChemicalComet assayCytotoxicityGenotoxicityMicronucleus assaySantos-São Vicente estuary

Identifiers

PMID31982997
OpenAlexW3000840571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.