ArticleEuropean journal of epidemiology2020
Radiation risk of central nervous system tumors in the Life Span Study of atomic bomb survivors, 1958-2009.
Article in European journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Association Between Meningioma and Breast Cancer: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- Ionizing radiation exposure during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis.Scientific reports · 2022Pooled it
- EANO guideline on the diagnosis and management of meningiomas.Neuro-oncology · 2021Guideline
- Radiation Exposure and Cancer Mortality in Populations Living Around the Semipalatinsk Nuclear Test Site in Kazakhstan.International journal of environmental research and public health · 2026Article
- Exogenous Hormones and Their Clinical Implications for the Development and Growth of Meningioma Tumours.Journal of clinical medicine · 2026Review
- Interpretation of Epidemiological Studies on the Relationship Between Mobile Phone Use and Cancer.Epidemiologia (Basel, Switzerland) · 2026Article
- Cancer incidence near nuclear facilities in Korea (2005-2022): implications of regional socioeconomic status and industrial context.BMC public health · 2026Article
- Occupational exposure to ionising radiation and central nervous system tumour mortality: a pooled analysis of Korean, French and US medical radiation workers.BMJ public health · 2026Article
- Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring.Carcinogenesis · 2025Review
- Comparison of radiation-related cancer risks from the atomic bomb survivors with studies of pediatric medical radiation exposure.Carcinogenesis · 2025Article
- Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958-2009.Carcinogenesis · 2025Article
- The importance of data from the atomic bomb survivors for international radiological protection.Carcinogenesis · 2025Article
- Brain tumors linked to Chernobyl radiation exposure: a case study and historical perspective. Illustrative cases.Journal of neurosurgery. Case lessons · 2025Article
- Trans-Scale Insights into Variability in Radiation Cancer Risk Across Tissues, Individuals, and Species.Biology · 2025Review
- The comparative burden of brain and central nervous system cancers from 1990 to 2021 between China, the United States, the United Kingdom, and Japan.BMC public health · 2025Article
- Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization.Scientific reports · 2025Article
- A note on potential gains in precision of radiation risk estimates from joint analysis.Scientific reports · 2024Article
- Establishment and activity of the planning and acting network for low dose radiation research in Japan (PLANET): 2016-2023.Journal of radiation research · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Risk of central nervous system tumour incidence in a cohort of workers chronically exposed to ionising radiation.Radiation and environmental biophysics · 2024Article
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10 authors.
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Abstract
Radiation exposure is among the few factors known to be associated with risk of central nervous system (CNS) tumors. However, the patterns of radiation risk by histological type, sex or age are unclear. We evaluated radiation risks of first primary glioma, meningioma, schwannoma, and other or not otherwise specified (other/NOS) tumors in the Life Span Study cohort of atomic bomb survivors. Cases diagnosed between 1958 and 2009 were ascertained through population-based cancer registries in Hiroshima and Nagasaki. To estimate excess relative risk per Gy (ERR/Gy), we fit rate models using Poisson regression methods. There were 285 CNS tumors (67 gliomas, 107 meningiomas, 49 schwannomas, and 64 other/NOS tumors) among 105,444 individuals with radiation dose estimates to the brain contributing 3.1 million person-years of observation. Based on a simple linear model without effect modification, ERR/Gy was 1.67 (95% confidence interval, CI: 0.12 to 5.26) for glioma, 1.82 (95% CI: 0.51 to 4.30) for meningioma, 1.45 (95% CI: - 0.01 to 4.97) for schwannoma, and 1.40 (95% CI: 0.61 to 2.57) for all CNS tumors as a group. For each tumor type, the dose-response was consistent with linearity and appeared to be stronger among males than among females, particularly for meningioma (P = 0.045). There was also evidence that the ERR/Gy for schwannoma decreased with attained age (P = 0.002). More than 60 years after the bombings, radiation risks for CNS tumors continue to be elevated. Further follow-up is necessary to characterize the lifetime risks of specific CNS tumors following radiation exposure.
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