Evidence map›Paper›PMID 31982963›Full record

Trial reportWorld journal of urology2020

Paravertebral block for percutaneous nephrolithotomy: a prospective, randomized, double-blind placebo-controlled study.

Kristin G Baldea, Parth M Patel, Grace Delos Santos, Chandy Ellimoottil, Ahmer Farooq, Elizabeth R Mueller, Scott Byram, Thomas M T Turk

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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  11. Current advances in pain regimens for percutaneous nephrolithotomy A comprehensive review.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kristin G BaldeaDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA.
Parth M PatelDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA. Parth.Patel001@lumc.edu.ORCID http://orcid.org/0000-0002-8119-274X
Grace Delos SantosDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA.
Chandy EllimoottilDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
Ahmer FarooqDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA.
Elizabeth R MuellerDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA.
Scott ByramDepartment of Anesthesiology, Loyola University Medical Center, Maywood, IL, USA.
Thomas M T TurkDepartment of Urology, Loyola University Medical Center, Maywood, IL, 60153, USA.
Loyola University Medical Center · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePercutaneous nephrolithotomy (PCNL) is performed commonly in patients with large kidney stones, but the management of their postoperative pain presents a major challenge. While it is not routinely performed in PCNL patients, paravertebral block (PVB) has been described as an effective strategy for pain control after various non-urologic surgeries. This trial aims to assess the effect of paravertebral blockade on intraoperative and postoperative opioid use as well as postoperative pain control in patients undergoing PCNL.

methodsThis was a prospective, randomized, double-blind, placebo-controlled study. Patients who consented to participate were randomly assigned to undergo either PVB or a placebo intervention preoperatively. The patient, surgeon, and anesthesia team were all blinded to the randomization. The outcome parameters were intraoperative opioid requirement, postoperative visual analog scale (VAS) pain scores, postoperative opioid use, and postoperative antiemetic use.

results23 patients were enrolled in each arm of the study, and the two groups had no significant differences in baseline demographic or clinical characteristics. Patients in the PVB group had significantly lower intraoperative opioid use, postoperative opioid use, frequency of opioid use, and antiemetic. Patients in the PVB group also had lower postoperative VAS pain scores. There were no patients who suffered from complications attributable to PVB.

conclusionThe results of this randomized, double-blind, placebo-controlled trial suggest that PVB should be considered an effective strategy to reduce opioid requirement and improve pain control for patients undergoing PCNL.

Indexed as

Nephrolithotomy, PercutaneousAdultAgedDouble-Blind MethodFemaleHumansMaleMiddle AgedNerve BlockPostoperative PainProspective StudiesSpinal NervesNephrolithiasisNerve blockPain managementParavertebralPercutaneous nephrolithotomy

Identifiers

PMID31982963
OpenAlexW3000930444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.