ArticleComputer methods and programs in biomedicine2020
Three-dimensional biventricular strains in pulmonary arterial hypertension patients using hyperelastic warping.
Article in Computer methods and programs in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos.The Journal of physiology · 2024Article
- Right ventricular dyssynchrony predicts outcome in pulmonary arterial hypertension when assessed in multiple cardiac magnetic resonance views.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- An image registration framework to estimate 3D myocardial strains from cine cardiac MRI in mice.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2021Article
- Estimating cardiomyofiber strain in vivo by solving a computational model.Medical image analysis · 2021Article
- Current Understanding of the Right Ventricle Structure and Function in Pulmonary Arterial Hypertension.Frontiers in physiology · 2021Review
- Cardiac Magnetic Resonance Imaging in Pulmonary Arterial Hypertension: Ready for Clinical Practice and Guidelines?Current heart failure reports · 2020Review
- Reference Ranges for Left Ventricular Curvedness and Curvedness-Based Functional Indices Using Cardiovascular Magnetic Resonance in Healthy Asian Subjects.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
Abstract
BACKGROUND AND
objectiveEvaluation of biventricular function is an essential component of clinical management in pulmonary arterial hypertension (PAH). This study aims to examine the utility of biventricular strains derived from a model-to-image registration technique in PAH patients in comparison to age- and gender-matched normal controls.
methodsA three-dimensional (3D) model was reconstructed from cine short- and long-axis cardiac magnetic resonance (CMR) images and subsequently partitioned into right ventricle (RV), left ventricle (LV) and septum. The hyperelastic warping method was used to register the meshed biventricular finite element model throughout the cardiac cycle and obtain the corresponding biventricular circumferential, longitudinal and radial strains.
resultsIntra- and inter-observer reproducibility of biventricular strains was excellent with all intra-class correlation coefficients > 0.84. 3D biventricular longitudinal, circumferential and radial strains for RV, LV and septum were significantly decreased in PAH patients compared with controls. Receiver operating characteristic (ROC) analysis showed that the 3D biventricular strains were better early markers (Area under the ROC curve = 0.96 for RV longitudinal strain) of ventricular dysfunction than conventional parameters such as two-dimensional strains and ejection fraction.
conclusionsOur highly reproducible methodology holds potential for extending CMR imaging to characterize 3D biventricular strains, eventually leading to deeper understanding of biventricular mechanics in PAH.
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