ArticleMultiple sclerosis and related disorders2020
Socioeconomic deprivation increases the risk of disability in multiple sclerosis patients.
Article in Multiple sclerosis and related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Racial and ethnic disparities in pediatric autoimmune encephalitis: A systematic review.Multiple sclerosis and related disorders · 2025Pooled it
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- The Role of Lifestyle Factors in Multiple Sclerosis: An Integrative Perspective.Brain sciences · 2026Review
- Promoting Exercise as a Therapeutic Intervention in Multiple Sclerosis: Barriers, Efficacy, and Social Prescribing Strategies.Cardiology and cardiovascular medicine · 2026Article
- Health inequalities in outpatient neurological conditions across a large UK urban population: a retrospective observational study using automated coding.BMJ neurology open · 2026Article
- Socioeconomic inequalities in disability prevalence and health service use in Bangladesh.Scientific reports · 2025Article
- Stable excess mortality in a multiple sclerosis cohort diagnosed 1970-2010.European journal of neurology · 2024Article
- Early Adversity and Socioeconomic Factors in Pediatric Multiple Sclerosis: A Case-Control Study.Neurology(R) neuroimmunology & neuroinflammation · 2024Article
- Associations between socioeconomic inequalities and progression to psychological and cognitive multimorbidities after onset of a physical condition: a multicohort study.EClinicalMedicine · 2024Article
- Prevalence and Burden of Multiple Sclerosis in China, 1990-2019: Findings From the Global Burden of Disease Study 2019.Neurology · 2024Article
- Descriptive Analysis of Health Disparities Between Black and White People With Multiple Sclerosis in the Deep South.International journal of MS care · 2024Article
- Premorbid Sociodemographic Status and Multiple Sclerosis Outcomes in a Universal Health Care Context.JAMA network open · 2023Observational
- Economic and Social Standing of Individuals in Iran Diagnosed with Multiple Sclerosis.Archives of Iranian medicine · 2023Article
- Current Updates on the Diagnosis and Management of Multiple Sclerosis for the General Neurologist.Journal of clinical neurology (Seoul, Korea) · 2023Review
- Association Between Neighborhood Socioeconomic Status and 30-Day Mortality and Readmission for Patients With Common Neurologic Conditions.Neurology · 2023Article
- Effects of socioeconomic status on excess mortality in patients with multiple sclerosis in France: A retrospective observational cohort study.The Lancet regional health. Europe · 2023Article
- Social determinants of health in multiple sclerosis.Nature reviews. Neurology · 2022Review
- The impact of socioeconomic status on subsequent neurological outcomes in multiple sclerosis.Multiple sclerosis and related disorders · 2022Article
- Socioeconomic disparity is associated with faster retinal neurodegeneration in multiple sclerosis.Brain : a journal of neurology · 2021Article
- Validation of Discrete and Regression-Based Performance and Cognitive Fatigability Normative Data for the Paced Auditory Serial Addition Test in Multiple Sclerosis.Frontiers in neuroscience · 2021Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about the association between the socioeconomic status (SES) and disability risk of patients with Multiple Sclerosis (MS).
objectiveThe aim of this study was to assess the influence of low SES, otherwise known as socioeconomic deprivation, on the disability risk of MS patients.
methods4498 patients with a relapsing MS disease onset between 1982 and 2017 were included from the databases of three MS expert centres (Caen, Rouen, Lille) of the French Observatory for MS (OFSEP). Sociodemographic and clinical data of 3641 patients were used for the analysis. The EDI (European Deprivation Index), an ecological and composite indicator was used to assess the level of socioeconomic deprivation. Comparisons of time to reach EDSS 4 and EDSS 6, chosen as disability milestones, according to EDI quintiles were performed by Kaplan-Meier analysis. Cox proportional hazard models were also conducted to assess the risk according to EDI quintiles with adjustment to sex, MS type and age at disease onset.
resultsIn the study population (n = 3641), most patients were women (71.9%; n = 2664). The mean age at disease onset was 32.2 years (SD =9.7). 1684 (46%) patients reached EDSS 4 and 1005 (28%) reached EDSS 6. The risk of reaching EDSS 4 and EDSS 6 in more socioeconomically deprived patients (EDI Q5) was independently higher than in the less socioeconomically deprived patients (EDI Q1) (HR=1.37 95%CI [1.15-1.64]) to reach EDSS 4 and (HR=1.42 95%CI [1.13-1.75]) to reach EDSS 6.
conclusionsIn this study, socioeconomic deprivation was significantly associated to the disability risk in MS patients. Better knowledge of socioeconomic disparities in MS may help adapt care to settings and improve the quality of care given to patients in the future.
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