Evidence map›Paper›PMID 31982642›Full record

ArticleHearing research2020

Generation of a ChAT

Nichole L Beebe, Colleen S Sowick, Inga Kristaponyte, Alexander V Galazyuk, Douglas E Vetter, Brandon C Cox, Brett R Schofield

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hearing research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Sst- and Vip-Cre mouse lines without age-related hearing loss.bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nichole L BeebeDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: nbeebe@neomed.edu.
Colleen S SowickDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: cssowick@neomed.edu.
Inga KristaponyteDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: ikristaponyte@neomed.edu.
Alexander V GalazyukDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: agalaz@neomed.edu.
Douglas E VetterDepartment of Neurobiology and Anatomical Sciences, Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center Rm R730, 2500 N. State St, Jackson, MS, 39216, USA. Electronic address: DVetter@umc.edu.
Brandon C CoxDepartment of Pharmacology, Department of Otolaryngology, Southern Illinois University School of Medicine, 801 N. Rutledge Street, Springfield, IL, 62702, USA. Electronic address: bcox@siumed.edu.
Brett R SchofieldDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: bschofie@neomed.edu.
Northeast Ohio Medical University · USSouthern Illinois University School of Medicine · USUniversity of Mississippi Medical Center · US

Funding

Modulatory Circuits in the Auditory SystemR01DC004391 · NIDCD · UNIVERSITY OF LOUISVILLE · PI SCHOFIELD, BRETT R · 1999 to 2025
$9.9M
Neuronal hyperactivity: tinnitus and distressR01DC016918 · NIDCD · NORTHEAST OHIO MEDICAL UNIVERSITY · PI GALAZYUK, ALEXANDER · 2019 to 2023
$2.2M
NIDCD NIH HHS R01 DC004391NIDCD NIH HHS R01 DC016918
6 · The paper itself

Abstract

The development of knockin mice with Cre recombinase expressed under the control of the promoter for choline acetyltransferase (ChAT) has allowed experimental manipulation of cholinergic circuits. However, currently available ChAT

Indexed as

HearingAnimalsAuditory ThresholdBrain StemCadherinsCholine O-AcetyltransferaseCholinergic FibersCrosses, GeneticDNA-Binding ProteinsEvoked Potentials, Auditory, Brain StemFemaleGene Knock-In TechniquesHearing LossIntegrasesMaleMice, Inbred C57BLCadherinsCdh23 protein, mouseCholine O-AcetyltransferaseCre recombinaseDNA-Binding ProteinsIntegrasesNerve Tissue ProteinsNeuN protein, mouseAcetylcholineAge-related hearing lossCholine acetyltransferaseNormal hearingPresbycusisTransgenic mouse

Identifiers

PMID31982642
PMCPMC7369543
OpenAlexW3002790034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.