ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020
Inappropriate treatment of community-acquired pneumonia among children under five years of age in Tanzania.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Prevalence, associated factors and treatment prescriptions for community-acquired pneumonia: a cross-sectional study at the largest children's hospital in the Ashanti Region, Ghana.BMC infectious diseases · 2026Article
- Exosomal lncRNA DLEU2 aggravates inflammatory injury and apoptosis in pediatric viral pneumonia via the miR-330-5p.Hereditas · 2026Article
- Adapting global guidelines to local contexts: optimising community-acquired pneumonia (CAP) specific prescribing in Pakistan to counter antimicrobial resistance.BMJ open respiratory research · 2025Article
- The Burden of Hospitalization Due toHealth science reports · 2025Review
- Barriers to Compliance with National Guidelines Among Children Hospitalized with Community-Acquired Pneumonia in Vietnam and the Implications.Antibiotics (Basel, Switzerland) · 2025Article
- Bacterial isolates, antibiotic susceptibility, and determinants of positive blood culture in children with community-acquired pneumonia in Central Tanzania.The Pan African medical journal · 2025Article
- Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study.The Lancet. Child & adolescent health · 2024Observational
- A Narrative Review of Recent Antibiotic Prescribing Practices in Ambulatory Care in Tanzania: Findings and Implications.Medicina (Kaunas, Lithuania) · 2023Review
- Factors associated with caretakers' knowledge, attitude, and practices in the management of pneumonia for children aged five years and below in rural Uganda.BMC health services research · 2023Article
- What influences parental decisions about antibiotic use with their children: A qualitative study in rural Australia.PloS one · 2023Article
- Article
- Health System Considerations for Community-Based Implementation of Automated Respiratory Counters to Identify Childhood Pneumonia in 5 Regions of Ethiopia: A Qualitative Study.International journal of health policy and management · 2023Article
- Non-prescribed antibiotic use for children at community levels in low- and middle-income countries: a systematic review and meta-analysis.Journal of pharmaceutical policy and practice · 2022Article
- Drivers of irrational use of antibiotics among children: a mixed-method study among prescribers and dispensers in Tanzania.BMC health services research · 2022Article
- The global burden of hospitalisation due to pneumonia caused byEClinicalMedicine · 2022Article
- Nasopharyngeal Carriage and Antibiogram of Pneumococcal and Other Bacterial Pathogens from Children with Sickle Cell Disease in Tanzania.Infection and drug resistance · 2022Article
- Investigation of drug-related problems in patients hospitalized in chest disease wards: A randomized controlled trial.Frontiers in pharmacology · 2022Article
- Emerging Antimicrobial Drug Resistance in Africa and Latin America: Search for Reasons.Risk management and healthcare policy · 2022Review
- Multidrug-Resistant, Including Extended-Spectrum Beta Lactamase-Producing and Quinolone-Resistant,Antibiotics (Basel, Switzerland) · 2021Article
- Prevalence and Factors Associated with Parents Self-Medicating Under-Fives with Antibiotics in Bagamoyo District Council, Tanzania: a Cross-Sectional Study.Patient preference and adherence · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo describe the treatment of community-acquired pneumonia (CAP) in children under five years in Tanzania.
methodsBetween January and December 2017, children aged 2-59 months with chest radiography-confirmed CAP were enrolled. The parents were interviewed to collect information on the patients and home-based medication. Clinical information was derived from the patient files. Nasopharyngeal swab and blood samples were collected for isolation of the causative pathogens. Swab samples were analysed by quantitative PCR whereas blood samples were tested using BacT/Alert 3D.
resultsOverall, 109 children with CAP were included in this analysis. Provision of care to most children was delayed (median = 4.6 days). A quarter (26.6%) were given unprescribed/leftover antibiotics at home. Only one child had positive bacterial culture. Referrals were associated with nasopharyngeal carriage of Streptococcus pneumoniae (p = 0.003) and Haemophilus influenzae (p = 0.004). Of all admitted children, more than a quarter (n = 29) did not need to be hospitalised and inappropriately received injectable instead of oral antibiotics.
conclusionWe found high rates of home treatment, particularly with antibiotics. Appropriate health care was delayed for most children because of home treatment. Efforts are needed at the community level to improve awareness of antimicrobial resistance.
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