Evidence map›Paper›PMID 31982587›Full record

ArticleActa biomaterialia2020

Towards revealing key factors in mechanical instability of bioabsorbable Zn-based alloys for intended vascular stenting.

Ehsan Mostaed, Malgorzata Sikora-Jasinska, Morteza Shaker Ardakani, Ali Mostaed, Ian M Reaney, Jeremy Goldman, Jaroslaw W Drelich

Open access · greenAbstract read
In one paragraph

Article in Acta biomaterialia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 113 citations in OpenAlex.

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  10. Microstructural Control of Zn Alloy by Melt Spinning - A Novel Approach Towards Fabrication of Advanced Biodegradable Biomedical Materials.Materials science & engineering. A, Structural materials : properties, microstructure and processing · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ehsan MostaedDepartment of Materials Science and Engineering, Michigan Technological University, Houghton, MI 49931, USA. Electronic address: emostaed@mtu.edu.
Malgorzata Sikora-JasinskaDepartment of Materials Science and Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Morteza Shaker ArdakaniDepartment of Materials Science and Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Ali MostaedDepartment of Engineering Materials, University of Sheffield, Sheffield S1 3JD, UK; Department of Materials, University of Oxford, 16 Parks Road, Oxford OX1 3PH, UK.
Ian M ReaneyDepartment of Engineering Materials, University of Sheffield, Sheffield S1 3JD, UK.
Jeremy GoldmanDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Jaroslaw W DrelichDepartment of Materials Science and Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Michigan Technological University · USUniversity of Oxford · GBUniversity of Sheffield · GB

Funding

Corrosion Fatigue Resistant and Intimal Hyperplasia Suppressive Biometal for Bioabsorbable StentsR01HL144739 · NHLBI · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI DRELICH, JAROSLAW W · 2019 to 2021
$1.1M
NHLBI NIH HHS R01 HL144739
6 · The paper itself

Abstract

Zn-based alloys are recognized as promising bioabsorbable materials for cardiovascular stents, due to their biocompatibility and favorable degradability as compared to Mg. However, both low strength and intrinsic mechanical instability arising from a strong strain rate sensitivity and strain softening behavior make development of Zn alloys challenging for stent applications. In this study, we developed binary Zn-4.0Ag and ternary Zn-4.0Ag-xMn (where x = 0.2-0.6wt%) alloys. An experimental methodology was designed by cold working followed by a thermal treatment on extruded alloys, through which the effects of the grain size and precipitates could be thoroughly investigated. Microstructural observations revealed a significant grain refinement during wire drawing, leading to an ultrafine-grained (UFG) structure with a size of 700 nm and 200 nm for the Zn-4.0Ag and Zn-4.0Ag-0.6Mn, respectively. Mn showed a powerful grain refining effect, as it promoted the dynamic recrystallization. Furthermore, cold working resulted in dynamic precipitation of AgZn

Indexed as

Absorbable ImplantsStentsAlloysBlood VesselsCorrosionMaterials TestingSolutionsStress, MechanicalTensile StrengthX-Ray DiffractionZincAlloysSolutionsZincBiodegradableCorrosionPrecipitation softeningRoom temperature superplasticityZinc alloys

Identifiers

PMID31982587
PMCPMC7294534
OpenAlexW3002220951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.