ArticleSleep medicine2020
Maternal obstructive sleep apnea and neonatal birth outcomes in a population based sample.
Article in Sleep medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Diagnostic Accuracy of the Screening Questionnaires for Obstructive Sleep Apnoea in Pregnancy: A Meta-Analysis and Updated Systematic Review.Journal of sleep research · 2026Pooled it
- Effect of the maternal sleep disturbances and obstructive sleep apnea on feto-placental Doppler: A systematic review.Journal of sleep research · 2025Pooled it
- Continuous Positive Airway Pressure Treatment and Hypertensive Adverse Outcomes in Pregnancy: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Maternal sleep disordered breathing and offspring growth outcome: A systematic review and meta-analysis.Sleep medicine reviews · 2024Pooled it
- A Systematic Review of Studies Examining Associations between Sleep Characteristics with Dietary Intake and Eating Behaviors during Pregnancy.Nutrients · 2023Pooled it
- The association between adverse perinatal outcomes, obstructive sleep apnoea and the role of depressive symptoms.BMC pregnancy and childbirth · 2026Observational
- Sleep Disorders in Pregnant Women and Their Impact on Maternal and Fetal Outcomes: A Narrative Review.Journal of clinical medicine · 2026Review
- Baseline bicarbonate level is associated with apnea of prematurity in preterm neonates with neonatal jaundice: insights from the Medical Information Mart for Intensive Care III (MIMIC-III) database.Translational pediatrics · 2026Article
- Obstructive Sleep Apnea in Pregnancy and its Impact on Maternal-Fetal Health: A Hidden Threat - Narrative Review.The open respiratory medicine journal · 2025Review
- Article
- Gestational Intermittent Hypoxia Impairs ATJournal of biotechnology and biomedicine · 2024Article
- Adverse infant outcomes among women with sleep apnea or insomnia during pregnancy: A retrospective cohort study.Sleep health · 2023Article
- Review
- Common sleep disorders in pregnancy: a review.Frontiers in medicine · 2023Review
- Maternal obesity: Perinatal implications.SAGE open medicine · 2023Review
- Sleep disordered breathing and the risk of severe maternal morbidity in women with preeclampsia: A population-based study.Pregnancy hypertension · 2022Article
- A Narrative Review of Sex and Gender Differences in Sleep Disordered Breathing: Gaps and Opportunities.Life (Basel, Switzerland) · 2022Review
- Article
- Impact of nasal dilator strips on measures of sleep-disordered breathing in pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Pulmonary Considerations for Pregnant Women.Clinics in chest medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveEvaluate the association of OSA with birth outcomes including the risk of congenital anomalies and the need for a higher level of clinical care at delivery.
methodsPopulation-based study that linked newborn records with maternal records. Data from 95 perinatal centers across all geographic census divisions of the U.S. of women with a delivery diagnosis from 2010 to 2014 whose records could be linked to the corresponding newborn record. An International Classification of Diseases, ninth Revision (ICD-9) code for sleep apnea was used to identify exposure and outcome variables. Univariate and multivariate logistic regression analyses were performed with a model that included substance use, obesity, diabetes, maternal co-morbidities, and pregnancy complications.
resultsIn this study, 1,423,099 maternal records were linked to live newborn records. OSA was associated with a higher risk for congenital anomalies in offspring (aOR 1.26, 1.11 to 1.43), with the highest risk being that of musculoskeletal anomalies (aOR 1.89, 1.16 to 3.07) after adjusting for comorbidities and potential teratogens. Neonates born to mothers with OSA were more likely to be admitted to the intensive care unit (25.3% vs. 8.1%, p < 0.001), require resuscitation (aOR 2.76, 1.35 to 5.64) and have a longer hospital stay (aOR 2.25, 1.85 to 2.65).
conclusionsAlthough our study does not establish causation, it is the first to demonstrate a higher risk of congenital anomalies and resuscitation at birth in neonates of mothers with OSA, emphasizing the importance of identifying OSA in pregnant women and women of reproductive age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.