Evidence map›Paper›PMID 31981444›Full record

ArticleJournal of diabetes investigation2020

Is visceral abdominal fat area a better indicator for hyperglycemic risk? Results from the Pinggu Metabolic Disease Study.

Fang Zhang, Yufeng Li, Yingxi Zhao, Xianghai Zhou, Linong Ji

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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  9. The Demographic Specific Abdominal Fat Composition and Distribution Trends in US Adults from 2011 to 2018.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Fang ZhangDepartment of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-3707-9272
Yufeng LiDepartment of Endocrinology and Metabolism, Beijing Pinggu Hospital, Beijing, China.
Yingxi ZhaoNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-4937-4703
Xianghai ZhouDepartment of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Linong JiDepartment of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Peking University · CNUniversity of Oxford · GB

Funding

Major Chronic Non-communicable Disease Prevention and Control Research, National Key R&D Program of China 2016YFC1304901Major Chronic Non-communicable Disease Prevention and Control Research, National Key R&D Program of China 2016YFC1305600Major Chronic Non-communicable Disease Prevention and Control Research, National Key R&D Program of China 2016YFC1305603
6 · The paper itself

Abstract

AIMS/

introductionThe aim of the present study was to analyze the strength of association between fasting plasma glucose (FPG), 2-h postprandial glucose (2h PPG), hemoglobin A1c (HbA1c), disposition index (DI) and nine anthropometrics measures, to explore the best indicator for hyperglycemia. MATERIALS AND

methodsAnalyses were based on the cross-sectional data of 3,572 adults from the Pinggu Metabolic Disease Study. Anthropometrics were measured, visceral fat area (VFA) and subcutaneous fat area were calculated using an abdominal computed tomography scan. Linear regression was used to analyze the association between FPG, 2h PPG, HbA1c, DI and nine anthropometrics measures (height, weight, waist circumference [WC], body mass index and waist-to-hip ratio [WHR], waist-to-height ratio, VFA, subcutaneous fat area, and visceral-to-subcutaneous ratio). Logistic regression was further carried out to understand the association between per standard increase and risk for hyperglycemia.

resultsHigher VFA and subcutaneous fat area were associated with higher FPG, 2h PPG, HbA1c and DI after adjusting for other covariates. The strongest association observed after adjustment was WC for FPG, with one standard deviation greater WC being associated with 1.70 increased odds; WHR for 2h PPG, with one standard deviation greater WHR being associated with 1.83 increased odds. The strength of the association between VFA and FPG, 2h PPG, HbA1c, and DI was less than WHR and WC, but slightly stronger than body mass index. Stratified analyses showed that VFA performs better as an anthropometrics indicator in predicting hyperglycemic risk in women than men.

conclusionsWHR and WC remain the best indicators for hyperglycemic risk among ahealthy Chinese population.

Indexed as

AdultAgedAnthropometryAsian PeopleBlood GlucoseBody Mass IndexCross-Sectional StudiesFastingFemaleGlycated HemoglobinHumansHyperglycemiaIntra-Abdominal FatLinear ModelsMaleMetabolic DiseasesBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanBody mass indexDiabetesVisceral fat

Identifiers

PMID31981444
PMCPMC7378436
OpenAlexW3002670945

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.