Evidence map›Paper›PMID 31981229›Full record

ArticleJournal of medical virology2020

Molecular epidemiology of norovirus outbreaks in Argentina, 2013-2018.

Juan I Degiuseppe, Leslie Barclay, Karina A Gomes, Veronica Costantini, Jan Vinjé, Juan A Stupka

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  13. Development and validation of an efficient nomogram for risk assessment of norovirus infection in pediatric patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Juan I DegiuseppeDepartment of Virology, Laboratory of Viral Gastroenteritis, INEI-ANLIS "Dr. Carlos G. Malbrán", Buenos Aires, Argentina.
Leslie BarclayDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Karina A GomesDepartment of Virology, Laboratory of Viral Gastroenteritis, INEI-ANLIS "Dr. Carlos G. Malbrán", Buenos Aires, Argentina.
Veronica CostantiniDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0002-1532-4345
Jan VinjéDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Juan A StupkaDepartment of Virology, Laboratory of Viral Gastroenteritis, INEI-ANLIS "Dr. Carlos G. Malbrán", Buenos Aires, Argentina.
Administración Nacional de Laboratorios e Institutos de Salud · ARCenters for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Noroviruses are a leading cause of endemic and epidemic acute gastroenteritis in all age groups. However, in Latin America, there are limited and updated data regarding circulating genotypes. The aim of this study was to assess the prevalence and genetic diversity of norovirus outbreaks in Argentina from 2013 to 2018. Stool samples from 29 acute gastroenteritis (AGE) outbreaks were available for viral testing. Norovirus was detected in samples from 18 (62.1%) outbreaks (2 GI and 16 GII). Both GI outbreaks were typed as GI.6[P11] whereas 10 different GII genotypes were detected, in which GII.4 viruses were the most frequently detected (29.4%, associated with GII.P31 and GII.P16) followed by GII.1[P33] and GII.6[P7] (17.6% each). Like GII.4 viruses, GII.2 viruses were also detected in association with different polymerases (GII.P2 and GII.P16). Our findings underscore the importance of dual RNA-dependent RNA polymerase-VP1 typing since recombinant strains with new polymerase sequences emerge frequently suggesting a possible role in improved fitness of these viruses. This study represents the most recent multi-year assessment of the molecular epidemiology of norovirus strains associated with AGE outbreaks in Argentina. Molecular surveillance of norovirus has to be considered to monitor possible changes in dominant genotypes which may assist to inform the formulation of future vaccines.

Indexed as

ArgentinaCaliciviridae InfectionsDisease OutbreaksGastroenteritisGenotypeHumansMolecular EpidemiologyNorovirusPhylogenyRNA, ViralRNA, Viralacute gastroenteritis outbreaksmolecular epidemiologyNorovirus

Identifiers

PMID31981229
PMCPMC8978480
OpenAlexW3001971894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.