Evidence map›Paper›PMID 31980990›Full record

ArticleJournal of computational neuroscience2020

A calcium-influx-dependent plasticity model exhibiting multiple STDP curves.

Akke Mats Houben, Matthias S Keil

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of computational neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Akke Mats HoubenInstitute of Neurosciences and Faculty for Psychology, University of Barcelona, Passeig de la Vall d'Hebron 171, 08035, Barcelona, Spain. akkehouben@gmail.com.ORCID 0000-0002-8215-7882
Matthias S KeilInstitute of Neurosciences and Faculty for Psychology, University of Barcelona, Passeig de la Vall d'Hebron 171, 08035, Barcelona, Spain.ORCID 0000-0003-1035-4446
Universitat de Barcelona · ESVall d'Hebron Institut de Recerca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hebbian plasticity means that if the firing of two neurons is correlated, then their connection is strengthened. Conversely, uncorrelated firing causes a decrease in synaptic strength. Spike-timing-dependent plasticity (STDP) represents one instantiation of Hebbian plasticity. Under STDP, synaptic changes depend on the relative timing of the pre- and post-synaptic firing. By inducing pre- and post-synaptic firing at different relative times the STDP curves of many neurons have been determined, and it has been found that there are different curves for different neuron types or synaptic sites. Biophysically, strengthening (long-term potentiation, LTP) or weakening (long-term depression, LTD) of glutamatergic synapses depends on the post-synaptic influx of calcium (Ca

Indexed as

Models, NeurologicalAlgorithmsCalcium SignalingComputer SimulationElectrophysiological PhenomenaGlutamatesHumansLong-Term PotentiationMembrane PotentialsNeuronal PlasticityNeuronsNeurotransmitter AgentsReceptors, AMPAReceptors, N-Methyl-D-AspartateGlutamatesNeurotransmitter AgentsReceptors, AMPAReceptors, N-Methyl-D-AspartateCalcium-dependent-plasticitySTDPSynaptic plasticity

Identifiers

PMID31980990
OpenAlexW3001129069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.