Evidence map›Paper›PMID 31980908›Full record

ArticleMikrochimica acta2020

Analysis of glycan expression on cell surfaces by using a glassy carbon electrode modified with MnO

Kejun Feng, Fangli Liao, Minghui Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kejun FengSchool of Chemistry and Materials Engineering, Huizhou University, Huizhou, 516007, Guangdong, China. hndxfkj@hotmail.com.
Fangli LiaoSchool of Chemistry and Materials Engineering, Huizhou University, Huizhou, 516007, Guangdong, China.
Minghui YangCollege of Chemistry and Chemical Engineering, Hunan Provincial Key Laboratory of Efficient and Clean Utilization of Manganese Resources, Central South University, Changsha, 410083, China.
Huizhou University · CNCentral South University · CN

Funding

Hunan Provincial Science and Technology Plan Project, China 2016TP1007
6 · The paper itself

Abstract

Electrochemical assay for analysis of cell surface glycan expression is reported. Mannose on human breast cancer cells (type MCF-7) is selected as the glycan model. Gold nanoparticles are modified with binding aptamer for MCF-7 cells and act as electrochemical probe. The analysis of cell surface glycan expression follows a traditional sandwich protocol. Concanavalin A that can specifically recognize mannose is immobilized onto MnO

Indexed as

Manganese CompoundsOxidesAptamers, NucleotideCarbonCell Line, TumorCell MembraneDNAElectrochemical TechniquesElectrodesGoldHumansLimit of DetectionMCF-7 CellsMetal NanoparticlesMolybdenumPolysaccharidesAptamers, NucleotideCarbonDNAGoldManganese Compoundsmanganese dioxidemolybdateMolybdenumOxidesPolysaccharidesAptamerConcanavalin AGold nanoparticleMannoseMolybdate

Identifiers

PMID31980908
OpenAlexW3002598714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.