Evidence map›Paper›PMID 31980857›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats.

Hao Wang, Xiao-Yan Gao, Fang Rao, Hui Yang, Zhao-Yu Wang, Lin Liu, Su-Juan Kuang, Qi Wu, Chun-Yu Deng, Jing-Song Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hao Wang *Department of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, People's Republic of China.ORCID http://orcid.org/0000-0002-3380-8976
Xiao-Yan Gao *Guangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Fang RaoGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Hui YangGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Zhao-Yu WangGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Lin LiuGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Su-Juan KuangGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China.
Qi WuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, People's Republic of China.
Chun-Yu DengGuangdong Provincial Key Laboratory of Clinical Pharmacology, Department of Cardiology, Guangdong Cardiovascular Institute, Guangzhou, 510080, China. chunyudeng@126.com.
Jing-Song XuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, People's Republic of China. xujingsong@medmail.com.cn.
Guangdong Academy of Medical Sciences · CNNanchang University · CNKey Laboratory of Guangdong Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is one of the risk factors for coronary heart disease. The present study investigated the mechanism of contractile dysfunction induced by serotonin (5-HT) in coronary artery in spontaneously hypertensive rats (SHRs). Coronary arteries were isolated form SHRs and Wistar rats. Arterial ring contraction was measured using a multi myograph system. Intracellular calcium concentration was measured with a Ca

Indexed as

AnimalsCalciumCalcium SignalingCells, CulturedCoronary VesselsDisease Models, AnimalHypertensionMaleMuscle, Smooth, VascularMyocytes, Smooth MuscleRats, Inbred SHRRats, WistarReceptor, Serotonin, 5-HT2ASerotoninSerotonin 5-HT2 Receptor AgonistsVasoconstrictionCalciumReceptor, Serotonin, 5-HT2ASerotoninSerotonin 5-HT2 Receptor Agonists5-HTCoronary arteryHypertensionSpontaneously hypertensive ratsVasoconstriction

Identifiers

PMID31980857
OpenAlexW3001343030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.