Evidence map›Paper›PMID 31980738›Full record

ReviewExperimental & molecular medicine2020

Amino acids in cancer.

Elizabeth L Lieu, Tu Nguyen, Shawn Rhyne, Jiyeon Kim

Open access · goldAbstract readReview
In one paragraph

Review in Experimental & molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 479 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
479citing papers in PubMed, 3 pooled it
49.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

479 citing papers in PubMed, 3 syntheses or guidelines pooled it, 815 citations in OpenAlex.

  1. Colorectal neoplasia-specific amino acid profiles and their diagnostic potential: a systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
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  5. NMR in biomedicine · 2026
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419 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elizabeth L Lieu *Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
Tu Nguyen *Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
Shawn Rhyne *Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.
Jiyeon KimDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA. jiyeonk@uic.edu.
University of Illinois Chicago · US

Funding

Targeting altered nitrogen metabolism in an aggressive subset of human lung canceK22CA226676 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KIM, JIYEON · 2019 to 2021
$591k
American Lung Association (Lung Association) LCD-614827NCI NIH HHS K22 CA226676U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) 1K22CA226676-01A1V Foundation for Cancer Research (V Foundation) V2019-022
6 · The paper itself

Abstract

Over 90 years ago, Otto Warburg's seminal discovery of aerobic glycolysis established metabolic reprogramming as one of the first distinguishing characteristics of cancer

Indexed as

Amino AcidsAnimalsEpigenesis, GeneticHumansNeoplasmsTumor MicroenvironmentAmino Acids

Identifiers

PMID31980738
PMCPMC7000687
OpenAlexW3002071299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.