ArticleScientific reports2020
Comprehensive Behavioral Intervention for Tics reduces perception-action binding during inhibitory control in Gilles de la Tourette syndrome.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions.European child & adolescent psychiatry · 2022Guideline
- Functional connectivity during tic suppression predicts reductions in vocal tics following behavior therapy in children with Tourette syndrome.Psychological medicine · 2023Trial
- The Impact of Provider Goals, Perceptions, and Beliefs on the Delivery of Comprehensive Behavioral Intervention for Tics.Child psychiatry and human development · 2026Article
- Evidence-Based Behavior Therapy for Tourette Syndrome.The Psychiatric clinics of North America · 2025Review
- Altered network connectivity and global efficiency in tourette syndrome: insights into sensorimotor integration.NeuroImage. Clinical · 2025Article
- Differential modulation of neural oscillations in perception-action links in Tourette syndrome.Brain communications · 2025Article
- [Advances in the application of comprehensive behavioral intervention in tic disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- A narrative review to guide treatment and care for children with Tourette syndrome.Brain disorders (Amsterdam, Netherlands) · 2023Article
- Cognitive and Neural Mechanisms of Behavior Therapy for Tics: A Perception-Action Integration Approach.Biomedicines · 2023Review
- Molecular Landscape of Tourette's Disorder.International journal of molecular sciences · 2023Article
- Tourette Syndrome Treatment Updates: a Review and Discussion of the Current and Upcoming Literature.Current neurology and neuroscience reports · 2022Review
- Overcoming the phenomenological Perpetuum mobile in clinical cognitive neuroscience for the benefit of replicability in research and the societal view on mental disorders.Frontiers in human neuroscience · 2022Article
- Tourette syndrome research highlights from 2020.F1000Research · 2022Review
- Towards an Ideology-Free, Truly Mechanistic Health Psychology.International journal of environmental research and public health · 2021Article
- Increased scale-free and aperiodic neural activity during sensorimotor integration-a novel facet in Tourette syndrome.Brain communications · 2021Article
- Access to Procedural Memories After One Year: Evidence for Robust Memory Consolidation in Tourette Syndrome.Frontiers in human neuroscience · 2021Article
- Electrophysiology Echoes Brain Dynamics in Children and Adolescents With Tourette Syndrome-A Developmental Perspective.Frontiers in neurology · 2021Review
- Non-invasive Brain Stimulation for the Treatment of Gilles de la Tourette Syndrome.Frontiers in neurology · 2020Review
- Gilles de la Tourette Syndrome-A Disorder of Action-Perception Integration.Frontiers in neurology · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gilles de la Tourette Syndrome (GTS) is a developmental disorder. Empirical studies and an emerging cognitive framework on GTS suggest that GTS is a disorder of abnormally strong 'perception-action binding'. Theoretical considerations imply that the effectiveness of long-established behavioral interventions might be related to a normalization of increased binding in GTS. This has not been tested yet. We examined the effect of a standardized Comprehensive Behavior Intervention for Tics (CBIT) in N = 21 adolescent GTS patients and N = 21 healthy controls on perception-action binding in an inhibitory control paradigm. Prior to CBIT, GTS patients showed compromised performance compared to controls, specifically when inhibitory control was triggered by uni-modal visual compared to bi-modal stimuli. After CBIT intervention, GTS patient's performance was at the same level as healthy controls. This is supported by a Bayesian data analysis. CBIT specifically affected inhibitory control in a condition where reconfigurations of perception-action bindings are necessary to perform inhibitory control. A power of 95% was evident for these effects. CBIT reduces increased 'binding' between perception and action in GTS and thereby increases the ability to perform response inhibition. The results are the first to provide insights as to why CBIT is effective by relating elements of this intervention to overarching cognitive theoretical frameworks on perception-action bindings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.