Evidence map›Paper›PMID 31980663›Full record

ArticleScientific reports2020

Adenylosuccinic acid therapy ameliorates murine Duchenne Muscular Dystrophy.

Cara A Timpani, Craig A Goodman, Christos G Stathis, Jason D White, Kamel Mamchaoui, Gillian Butler-Browne, Nuri Gueven, Alan Hayes, Emma Rybalka

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Evaluation of Creatine Monohydrate Supplementation on the Gastrocnemius Muscle of Mice with Muscular Dystrophy: A Preliminary Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Adenylosuccinic Acid: An Orphan Drug with Untapped Potential.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Silibinin reducesFrontiers in microbiology · 2023
    Article
  15. Review
  16. Biomarkers in Duchenne Muscular Dystrophy.Current heart failure reports · 2022
    Review
  17. Reducing sarcolipin expression improves muscle metabolism inAmerican journal of physiology. Cell physiology · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Cara A TimpaniInstitute for Health and Sport, Victoria University, Melbourne, Victoria, 8001, Australia.
Craig A GoodmanInstitute for Health and Sport, Victoria University, Melbourne, Victoria, 8001, Australia.
Christos G StathisInstitute for Health and Sport, Victoria University, Melbourne, Victoria, 8001, Australia.
Jason D WhiteMurdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-0557-392X
Kamel MamchaouiInstitut de Myologie, Sorbonne University, INSERM UMRS974, Paris, France.
Gillian Butler-BrowneInstitut de Myologie, Sorbonne University, INSERM UMRS974, Paris, France.
Nuri GuevenPharmacy, School of Medicine, University of Tasmania, Hobart, Tasmania, 7000, Australia.
Alan HayesInstitute for Health and Sport, Victoria University, Melbourne, Victoria, 8001, Australia.
Emma RybalkaInstitute for Health and Sport, Victoria University, Melbourne, Victoria, 8001, Australia. emma.rybalka@vu.edu.au.ORCID http://orcid.org/0000-0002-4854-0036
Australian Institute for Musculoskeletal Science · AUInserm · FRRoyal Children's Hospital · AUUniversity of Tasmania · AUVictoria University · AUWestern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arising from the ablation of the cytoskeletal protein dystrophin, Duchenne Muscular Dystrophy (DMD) is a debilitating and fatal skeletal muscle wasting disease underpinned by metabolic insufficiency. The inability to facilitate adequate energy production may impede calcium (Ca

Indexed as

Adenosine MonophosphateAnimalsCalciumCell Line, TransformedCollagenDrug Evaluation, PreclinicalElectron TransportHumansLipidsMaleMiceMice, Inbred C57BLMice, Inbred mdxMitochondria, MuscleMuscle, SkeletalMuscular Dystrophy, AnimalAdenosine MonophosphateadenylosuccinateCalciumCollagenLipidsSuperoxidesUtrn protein, mouseUtrophin

Identifiers

PMID31980663
PMCPMC6981178
OpenAlexW3001978981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.