Evidence map›Paper›PMID 31980655›Full record

ArticleNature communications2020

Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance.

Yuki Oe, Xiaowen Wang, Tommaso Patriarchi, Ayumu Konno, Katsuya Ozawa, Kazuko Yahagi, Hirokazu Hirai, Takashi Tsuboi, Tetsuya Kitaguchi, Lin Tian and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 167 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Crosstalk of noradrenergic CaCell communication and signaling : CCS · 2026
    Article
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Yuki OeRIKEN Center for Brain Science, Wako, Saitama, Japan. oe@brain.riken.jp.
Xiaowen WangRIKEN Center for Brain Science, Wako, Saitama, Japan.
Tommaso PatriarchiDepartment of Biochemistry and Molecular Medicine, University of California, Davis, CA, USA.
Ayumu KonnoViral Vector Core, Gunma University Initiative for Advanced Research, Maebashi, Gunma, 371-8511, Japan.ORCID http://orcid.org/0000-0001-9382-396X
Katsuya OzawaRIKEN Center for Brain Science, Wako, Saitama, Japan.
Kazuko YahagiRIKEN Center for Brain Science, Wako, Saitama, Japan.
Hirokazu HiraiViral Vector Core, Gunma University Initiative for Advanced Research, Maebashi, Gunma, 371-8511, Japan.ORCID http://orcid.org/0000-0002-0721-4293
Takashi TsuboiDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo, 153-8902, Japan.
Tetsuya KitaguchiLaboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.
Lin TianDepartment of Biochemistry and Molecular Medicine, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0001-7012-6926
Thomas J McHughRIKEN Center for Brain Science, Wako, Saitama, Japan.ORCID http://orcid.org/0000-0002-1243-5189
Hajime HiraseRIKEN Center for Brain Science, Wako, Saitama, Japan. hirase@sund.ku.dk.ORCID http://orcid.org/0000-0003-3806-6905
RIKEN Center for Brain Science · JPGunma University · JPUniversity of Copenhagen · DKThe University of Tokyo · JPTokyo Institute of Technology · JPUniversity of California, Davis · USUniversity of Zurich · CH

Funding

Next generation all-optical toolkits for functional analysis of neuropeptide dynamics in neural circuitsU01NS113295 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANGHART, MATTHEW R., SABATINI, BERNARDO L · 2019 to 2022
$3.7M
Fluorescent biosensors for imaging neurotransmitters: observing synapses in actioDP2MH107056 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TIAN, LIN · 2014 to 2014
$2.3M
Genetically encoded sensors for the biogenic amine: watching neuromodulation in actionU01NS090604 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TIAN, LIN · 2014 to 2016
$1.3M
Opioid Sensitive GABA inputs to the Ventral MidbrainR01DA034388 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 2012 to 2016
$967k
NIDA NIH HHS R01 DA034388NIMH NIH HHS DP2 MH107056NINDS NIH HHS U01 NS090604
6 · The paper itself

Abstract

Astrocytes may function as mediators of the impact of noradrenaline on neuronal function. Activation of glial α1-adrenergic receptors triggers rapid astrocytic Ca

Indexed as

AnimalsArousalAstrocytesCalcium SignalingConditioning, ClassicalCyclic AMPFearFluorescent DyesLocus CoeruleusMemoryMiceNeuronal PlasticityNorepinephrineParietal LobeReceptors, AdrenergicSecond Messenger SystemsCyclic AMPFluorescent DyesNorepinephrineReceptors, Adrenergic

Identifiers

PMID31980655
PMCPMC6981284
OpenAlexW3002558744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.