Evidence map›Paper›PMID 31980636›Full record

ArticleNature communications2020

Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa.

Brian R Amman, Brian H Bird, Ibrahim A Bakarr, James Bangura, Amy J Schuh, Jonathan Johnny, Tara K Sealy, Immah Conteh, Alusine H Koroma, Ibrahim Foday and 40 more

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Article
  5. International journal of molecular sciences · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Brian R AmmanViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Brian H BirdOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Ibrahim A BakarrDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
James BanguraOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Amy J SchuhViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Jonathan JohnnyDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Tara K SealyViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Immah ContehDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Alusine H KoromaDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Ibrahim FodayDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Emmanuel AmaraUniversity of Makeni, Makeni, Sierra Leone.
Abdulai A BanguraUniversity of Makeni, Makeni, Sierra Leone.
Aiah A GbakimaMinistry of Technical and Higher Education, New England Ville, Freetown, Sierra Leone.
Alexandre Tremeau-BravardDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Manjunatha BelaganahalliDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Jasjeet DhanotaOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Andrew ChowOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Victoria OntiverosOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Alexandra GibsonOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Joseph TurayUniversity of Makeni, Makeni, Sierra Leone.
Ketan PatelViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
James GrazianoViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Camilla BanguraDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Emmanuel S KamandaDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Augustus OsborneDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Emmanuel SaiduDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Jonathan MusaDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Doris BanguraDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Samuel Maxwell Tom WilliamsDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Richard WadsworthDepartment of Biological Sciences, Njala University, Njala, Sierra Leone.
Mohamed TurayUniversity of Makeni, Makeni, Sierra Leone.
Lavalie EdwinUniversity of Makeni, Makeni, Sierra Leone.
Vanessa Mereweather-ThompsonUniversity of Makeni, Makeni, Sierra Leone.
Dickson KargboUniversity of Makeni, Makeni, Sierra Leone.
Fatmata V BairohUniversity of Makeni, Makeni, Sierra Leone.
Marilyn KanuUniversity of Makeni, Makeni, Sierra Leone.
Willie RobertUniversity of Makeni, Makeni, Sierra Leone.
Victor LungaiUniversity of Makeni, Makeni, Sierra Leone.
Raoul Emeric Guetiya WadoumUniversity of Makeni, Makeni, Sierra Leone.
Moinya CoomberUniversity of Makeni, Makeni, Sierra Leone.
Osman KanuUniversity of Makeni, Makeni, Sierra Leone.
Amara JambaiMinistry of Health and Sanitation, Brookfields, Freetown, Sierra Leone.
Sorie M KamaraMinistry of Agriculture and Forestry, Brookfields, Freetown, Sierra Leone.
Celine H TaboyViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Tushar SinghCenter for Global Health, Centers for Disease Control and Prevention, Freetown, Sierra Leone.
Jonna A K MazetOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA.
Stuart T NicholViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA.
Tracey GoldsteinOne Health Institute, School of Veterinary Medicine, University of California, 1089 Veterinary Medicine Drive VetMed 3B, Ground Floor West, Davis, CA, 95616, USA. tgoldstein@ucdavis.edu.ORCID http://orcid.org/0000-0002-1672-7410
Jonathan S TownerViral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA, 30329, USA. jit8@cdc.gov.ORCID http://orcid.org/0000-0002-6473-3049
Aiah LebbieDepartment of Biological Sciences, Njala University, Njala, Sierra Leone. alebbie@njala.edu.sl.ORCID http://orcid.org/0000-0001-8725-3593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus aegyptiacus) as a natural reservoir. However, the largest recorded MVD outbreak with the highest case-fatality ratio happened in 2005 in Angola, where direct spillover from bats was not  shown. Here, collaborative studies by the Centers for Disease Control and Prevention, Njala University, University of California, Davis USAID-PREDICT, and the University of Makeni identify MARV circulating in ERBs in Sierra Leone. PCR, antibody and virus isolation data from 1755 bats of 42 species shows active MARV infection in approximately 2.5% of ERBs. Phylogenetic analysis identifies MARVs that are similar to the Angola strain. These results provide evidence of MARV circulation in West Africa and demonstrate the value of pathogen surveillance to identify previously undetected threats.

Indexed as

Africa, WesternAnimalsCavesChiropteraGenome, ViralGeographyLikelihood FunctionsMarburgvirusMarburg Virus DiseasePhylogenySequence Analysis, DNAViral ProteinsViral Proteins

Identifiers

PMID31980636
PMCPMC6981187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.