ArticleNature communications2020
Ionophore constructed from non-covalent assembly of a G-quadruplex and liponucleoside transports K
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 60 citations in OpenAlex.
- G-quartet driven adaptive hydrogels that integrate constitutional dynamics for antibacterial action and tissue repair.iScience · 2026Article
- Membrane-Spanning Nanopores Formed from Nucleic Acids.Chemical reviews · 2026Review
- CuChemistry, an Asian journal · 2026Article
- Cation-Controlled Assembly, Activity, and Organization of Biomimetic DNA Receptors in Synthetic Cell Membranes.Journal of the American Chemical Society · 2025Article
- Molecular prosthetics for CFTR designed for anion selectivity outperform amphotericin B in cultured cystic fibrosis airway epithelia.bioRxiv : the preprint server for biology · 2025Article
- Enhancing G-quadruplex-based DNA nanotechnology: new lipophilic DNA G-quadruplexes with TBDPS modifications.RSC advances · 2025Article
- Intermolecular Structure Conversion-Based G4-TDF Nanostructures Functionalized μPADs for Fluorescent Determination of Potassium Ion in Serum.Biosensors · 2025Article
- Oriented triplex DNA as a synthetic receptor for transmembrane signal transduction.Nature communications · 2024Article
- A non-B DNA binding peptidomimetic channel alters cellular functions.Nature communications · 2024Article
- Design and Synthesis of Covalently Tethered "IsoG-Star" as Recyclable Host for Selective Cesium Separation.Green chemistry : an international journal and green chemistry resource : GC · 2023Article
- Article
- Cholesterol-stabilized membrane-active nanopores with anticancer activities.Nature communications · 2022Article
- Digging into the biophysical features of cell membranes with lipid-DNA conjugates.Quarterly reviews of biophysics · 2022Review
- Heterocycle-modified 2'-Deoxyguanosine Nucleolipid Analogs Stabilize Guanosine Gels and Self-assemble to Form Green Fluorescent Gels.Chemistry, an Asian journal · 2022Article
- Mechanistic Understanding from Molecular Dynamics in Pharmaceutical Research 2: Lipid Membrane in Drug Design.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021Review
- Cholate Conjugated Polymeric Amphiphiles as Efficient Artificial Ionophores.ACS applied polymer materials · 2021Article
- G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection.Biosensors & bioelectronics · 2020Review
- Development of Artificial Cell Models Using Microfluidic Technology and Synthetic Biology.Micromachines · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The selective transport of ions across cell membranes, controlled by membrane proteins, is critical for a living organism. DNA-based systems have emerged as promising artificial ion transporters. However, the development of stable and selective artificial ion transporters remains a formidable task. We herein delineate the construction of an artificial ionophore using a telomeric DNA G-quadruplex (h-TELO) and a lipophilic guanosine (MG). MG stabilizes h-TELO by non-covalent interactions and, along with the lipophilic side chain, promotes the insertion of h-TELO within the hydrophobic lipid membrane. Fluorescence assays, electrophysiology measurements and molecular dynamics simulations reveal that MG/h-TELO preferentially transports K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.