ArticleAging2020
Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- The role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration.Genes & diseases · 2026Review
- Inflammation impairs fertility and oocyte quality in systemic lupus erythematosus by triggering oxidative stress-mediated ferroptosis.Cell death & disease · 2026Article
- Deoxynivalenol induces ferroptosis via inhibiting glycolysis-H3K18la-STEAP3 axis to promote ovary damage in piglets.Communications biology · 2025Article
- The dynamics of DNA methylation, histone methylation and acetylation during oocyte aging in mammalian species and possible interventions to regulate them.Journal of assisted reproduction and genetics · 2025Review
- Impact of psychological stress on ovarian function: Insights, mechanisms and intervention strategies (Review).International journal of molecular medicine · 2025Review
- Oocyte and dietary supplements: a mini review.Frontiers in cell and developmental biology · 2025Review
- Review
- Intergenerational epigenetic inheritance mediated by MYS-2/MOF in the pathogenesis of Alzheimer's disease.iScience · 2024Article
- Melatonin attenuates scopolamine-induced cognitive dysfunction through SIRT1/IRE1α/XBP1 pathway.CNS neuroscience & therapeutics · 2024Article
- Integration of parallel metabolomics and transcriptomics reveals metabolic patterns in porcine oocytes during maturation.Frontiers in endocrinology · 2023Article
- Oxidative stress induces meiotic defects of oocytes in a mouse psoriasis model.Cell death & disease · 2022Article
- Mitochondria: emerging therapeutic strategies for oocyte rescue.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions.Human reproduction update · 2022Review
- Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply.Redox biology · 2022Article
- Mitochondrial Calcium Disorder Affects Early Embryonic Development in Mice through Regulating the ERK/MAPK Pathway.Oxidative medicine and cellular longevity · 2022Article
- Article
- Procyanidin B2 Protects Aged Oocytes Against Meiotic Defects Through Cortical Tension Modulation.Frontiers in veterinary science · 2022Article
- Exogenous Melatonin Directly and Indirectly Influences Sheep Oocytes.Frontiers in veterinary science · 2022Article
- Article
- Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress.Oxidative medicine and cellular longevity · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been widely reported that advanced maternal age impairs oocyte quality. To date, various molecules have been discovered to be involved in this process. However, prevention of fertility issues associated with maternal age is still a challenge. In the present study, we find that both
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.