Evidence map›Paper›PMID 31980523›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Conformational changes upon gating of KirBac1.1 into an open-activated state revealed by solid-state NMR and functional assays.

Reza Amani, Collin G Borcik, Nazmul H Khan, Derek B Versteeg, Maryam Yekefallah, Hoa Q Do, Heather R Coats, Benjamin J Wylie

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Molecular mechanisms of Kir channel gating.Biochemical Society transactions · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. OPTO: Automated Optimization for Solid-State NMR Spectroscopy.Journal of the American Chemical Society · 2025
    Article
  7. Article
  8. Solid-State NMRJournal of magnetic resonance (San Diego, Calif. : 1997) · 2024
    Article
  9. Coordination of bilayer properties by an inward-rectifier KJournal of structural biology: X · 2024
    Article
  10. Cooperative Gating of a KJournal of the American Chemical Society · 2024
    Article
  11. Article
  12. Specific Lipid Studies in Complex Membranes by Solid-State NMR Spectroscopy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza AmaniDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Collin G BorcikDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Nazmul H KhanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Derek B VersteegDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Maryam YekefallahDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Hoa Q DoDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Heather R CoatsDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Benjamin J WylieDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409 benjamin.j.wylie@ttu.edu.ORCID 0000-0001-8183-2762

Funding

The Purchase of a Liquid Chromatography System to facilitate the high-throughput quantification of lipid-protein interactions and membrane ordering using solid-state NMRR35GM124979 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Benjamin James Wylie · 2017 to 2026
$3.6M
NIGMS NIH HHS R35 GM124979
6 · The paper itself

Abstract

The conformational changes required for activation and K

Indexed as

Bacterial ProteinsCatalytic DomainFluorescence Resonance Energy TransferKineticsMagnetic Resonance SpectroscopyModels, MolecularPhosphatidylcholinesPhosphatidylglycerolsPotassiumPotassium Channels, Inwardly RectifyingProtein ConformationProtein DomainsProtein Structure, Secondary1-palmitoyl-2-oleoylglycero-3-phosphoglycerol1-palmitoyl-2-oleoylphosphatidylcholineBacterial ProteinsKCNJ1 protein, humanPhosphatidylcholinesPhosphatidylglycerolsPotassiumPotassium Channels, Inwardly Rectifyingallosterylipid activationmembrane proteinpotassium channelsolid-state NMR

Identifiers

PMID31980523
PMCPMC7022178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.