Evidence map›Paper›PMID 31980512›Full record

ArticleBMJ open2020

Blood pressure monitoring in high-risk pregnancy to improve the detection and monitoring of hypertension (the BUMP 1 and 2 trials): protocol for two linked randomised controlled trials.

Greig Dougall, Marloes Franssen, Katherine Louise Tucker, Ly-Mee Yu, Lisa Hinton, Oliver Rivero-Arias, Lucy Abel, Julie Allen, Rebecca Jane Band, Alison Chisholm and 16 more

Erratum issued Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03334149 (Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03334149 nacompletednot on this map

Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension

TypeinterventionalSponsorUniversity of OxfordRan2017 to 2020Enrolled3,042ConditionsPregnancy, High Risk, Pre-Eclampsia, Hypertension, Hypertension, Pregnancy-InducedArmsSelf-Monitoring of Blood Pressure
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Setting and techniques for monitoring blood pressure during pregnancy.The Cochrane database of systematic reviews · 2020
    Pooled it
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  18. Hypertension in Women Across the Lifespan.Current atherosclerosis reports · 2021
    Review
  19. Maternal medicine in the COVID era.Best practice & research. Clinical obstetrics & gynaecology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 7 institutions in 1 country.

Greig DougallNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-9751-1998
Marloes FranssenNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Katherine Louise TuckerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0001-6544-8066
Ly-Mee YuNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Lisa HintonNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-6082-3151
Oliver Rivero-AriasNational Perinatal Epidemiology Unit (NPEU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Lucy AbelNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Julie AllenNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Rebecca Jane BandAcademic Unit of Psychology, University of Southampton, Southampton, UK.ORCID 0000-0001-5403-1708
Alison ChisholmNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Carole CrawfordNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Marcus GreenAction on Pre-eclampsia, Evesham, UK.
Sheila GreenfieldPrimary Care Clinical Sciences, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
James HodgkinsonPrimary Care Clinical Sciences, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Paul LeesonCardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK.
Christine McCourtCentre for Maternal & Child Health Research, School of Health Sciences, City University, London, UK.
Lucy MacKillopNuffield Department of Women's & Reproductive Health, Oxford University Hospitals NHS Trust, Oxford, UK.ORCID 0000-0002-1927-1594
Alecia NicklessNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Jane SandallDepartment of Women and Children's Health, Kings College, London, London, UK.
Mauro SantosInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Lionel TarassenkoInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Carmelo VelardoInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Hannah WilsonDepartment of Women and Children's Health, Kings College, London, London, UK.
Lucy YardleyAcademic Unit of Psychology, University of Southampton, Southampton, UK.
Lucy ChappellDepartment of Women and Children's Health, Kings College, London, London, UK lucy.chappell@kcl.ac.uk.
Richard J McManusNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0003-3638-028X
University of Oxford · GBKing's College London · GBUniversity of Birmingham · GBAction for ME · GBCity, University of London · GBUniversity of Bristol · GBUniversity of Southampton · GB

Funding

British Heart Foundation FS/19/7/34148Department of Health NIHR-RP-02-12-015Department of Health RP-2014-05-019Department of Health RP-PG-0614-20005
6 · The paper itself

Abstract

introductionSelf-monitoring of blood pressure (BP) in pregnancy could improve the detection and management of pregnancy hypertension, while also empowering and engaging women in their own care. Two linked trials aim to evaluate whether BP self-monitoring in pregnancy improves the detection of raised BP during higher risk pregnancies (BUMP 1) and whether self-monitoring reduces systolic BP during hypertensive pregnancy (BUMP 2). METHODS AND ANALYSES: Both are multicentre, non-masked, parallel group, randomised controlled trials. Participants will be randomised to self-monitoring with telemonitoring or usual care. BUMP 1 will recruit a minimum of 2262 pregnant women at higher risk of pregnancy hypertension and BUMP 2 will recruit a minimum of 512 pregnant women with either gestational or chronic hypertension. The BUMP 1 primary outcome is the time to the first recording of raised BP by a healthcare professional. The BUMP 2 primary outcome is mean systolic BP between baseline and delivery recorded by healthcare professionals. Other outcomes will include maternal and perinatal outcomes, quality of life and adverse events. An economic evaluation of BP self-monitoring in addition to usual care compared with usual care alone will be assessed across both study populations within trial and with modelling to estimate long-term cost-effectiveness. A linked process evaluation will combine quantitative and qualitative data to examine how BP self-monitoring in pregnancy is implemented and accepted in both daily life and routine clinical practice. ETHICS AND DISSEMINATION: The trials have been approved by a Research Ethics Committee (17/WM/0241) and relevant research authorities. They will be published in peer-reviewed journals and presented at national and international conferences. If shown to be effective, BP self-monitoring would be applicable to a large population of pregnant women. TRIAL REGISTRATION NUMBER: NCT03334149.

Indexed as

Pregnancy Complications, CardiovascularPregnancy, High-RiskQuality of LifeAdultBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleFollow-Up StudiesHumansHypertensionMulticenter Studies as TopicPre-EclampsiaPregnancyProspective StudiesRandomized Controlled Trials as TopicTelemedicineblood pressuregestational hypertensionhypertensionpre-eclampsiapregnancyself-monitoring

Identifiers

PMID31980512
PMCPMC7044851
OpenAlexW3001782777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.