Evidence map›Paper›PMID 31980503›Full record

ArticleCold Spring Harbor molecular case studies2020

Functional characterization of two rare BCR-FGFR1

Evan J Barnes, Jessica Leonard, Bruno C Medeiros, Brian J Druker, Cristina E Tognon

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Identifying Drug Combination Strategies forPrecision oncogenomics · 2025
    Article
  2. Acute Lymphoblastic Leukemia Characterized by RareCase reports in hematology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Myeloid Neoplasm with t(8;22)(p11;q11): A Mimicker of Chronic Myeloid Leukaemia in Blast Crisis.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Evan J BarnesDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon 97239, USA.
Jessica LeonardDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon 97239, USA.
Bruno C MedeirosDepartment of Medicine-Hematology, Stanford University, Stanford, California 94305, USA.ORCID 0000-0001-6972-8137
Brian J DrukerDivision of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon 97239, USA.
Cristina E TognonDepartment of Medicine-Hematology, Stanford University, Stanford, California 94305, USA.ORCID 0000-0002-4872-3078
Howard Hughes Medical Institute · USOregon Health & Science University · USStanford University · US

Funding

Functional Genomic Discovery of Pathway Targeted and Immune Modulatory Therapeutic Combinations in Hematologic MalignanciesU01CA217862 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI DRUKER, BRIAN J, TYNER, JEFFREY WALLACE · 2017 to 2021
$5.3M
An Academic-Industry Partnership to Advance Functional Genomics for Personalized Oncology.R01CA214428 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KEMP, CHRISTOPHER J · 2018 to 2022
$3.0M
NCI NIH HHS R01 CA214428NCI NIH HHS U01 CA217862
6 · The paper itself

Abstract

8p11 myeloproliferative syndrome (EMS) represents a unique World Health Organization (WHO)-classified hematologic malignancy defined by translocations of the FGFR1 receptor. The syndrome is a myeloproliferative neoplasm characterized by eosinophilia and lymphadenopathy, with risk of progression to either acute myeloid leukemia (AML) or T- or B-lymphoblastic lymphoma/leukemia. Within the EMS subtype, translocations between

Indexed as

Biomarkers, TumorBiopsyCombined Modality TherapyDisease ManagementDisease SusceptibilityFatal OutcomeFemaleHumansIn Situ Hybridization, FluorescenceKaryotypeLeukemiaMaleMiddle AgedOncogene Proteins, FusionProto-Oncogene Proteins c-bcrReceptor, Fibroblast Growth Factor, Type 1BCR protein, humanBiomarkers, TumorFGFR1 protein, humanOncogene Proteins, FusionProto-Oncogene Proteins c-bcrReceptor, Fibroblast Growth Factor, Type 1acute myeloid leukemiahematological neoplasm

Identifiers

PMID31980503
PMCPMC7133745
OpenAlexW3001558522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.