Evidence map›Paper›PMID 31980006›Full record

ArticlemAbs

Eugenio Gallo, Abdellali Kelil, Peter E Bayliss, Ajitha Jeganathan, Olga Egorova, Lynda Ploder, Jarret A Adams, Patricia Giblin, Sachdev S Sidhu

Open access · goldAbstract read
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy.International journal of peptide research and therapeutics · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Eugenio GalloDepartment of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.
Abdellali KelilDepartment of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.
Peter E BaylissNorthern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada.
Ajitha JeganathanNorthern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada.
Olga EgorovaNorthern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada.
Lynda PloderDepartment of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.
Jarret A AdamsDepartment of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.ORCID 0000-0002-0182-922X
Patricia GiblinNorthern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada.
Sachdev S SidhuDepartment of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.
University of Toronto · CAPrincess Margaret Cancer Centre · CA

Funding

CIHR MOP-136944
6 · The paper itself

Abstract

Integrins are transmembrane multi-conformation receptors that mediate interactions with the extracellular matrix. In cancer, integrins influence metastasis, proliferation, and survival. Collagen-binding integrin-α11/β1, a marker of aggressive tumors that is involved in stroma-tumor crosstalk, may be an attractive target for anti-cancer therapeutic antibodies. We performed selections with phage-displayed synthetic antibody libraries for binding to either purified integrin-α11/β1 or

Indexed as

Antibodies, MonoclonalIntegrin beta1AnimalsCell Surface Display TechniquesHumansIntegrin alpha ChainsMicePeptide LibraryAntibodies, MonoclonalIntegrin alpha ChainsIntegrin beta1ITGA11 protein, humanPeptide Libraryantibody selectionscancer therapeuticscellular selectionsEnhanced diversityintegrin-α11/β1 receptorITGA11

Identifiers

PMID31980006
PMCPMC6999838
OpenAlexW3001156896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.