Evidence map›Paper›PMID 31979980›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2020

Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.

Kang Wei, Jun Dai, Zhenggang Wang, Yaping Pei, Yan Chen, Yifan Ding, Qing Ding, Paerxiati Ahati, Xiaozhong Zhou, Huan Wang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Oxymatrine Protects Chondrocytes against IL-1Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  10. Ulinastatin Ameliorates IL-1Oxidative medicine and cellular longevity · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kang WeiDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Jun DaiDepartment of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.ORCID 0000-0001-5155-8838
Zhenggang WangDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Yaping PeiDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Yan ChenDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Yifan DingDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Qing DingDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Paerxiati AhatiDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Xiaozhong ZhouDepartment of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Huan WangDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.
Huang FangDepartment of Orthopaedics, Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-6204-6552
Tongji Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisAlkaloidsAnimalsCells, CulturedExtracellular MatrixInterleukin-1betaIntervertebral Disc DegenerationMatrinesMatrix MetalloproteinasesNF-kappa BNucleus PulposusQuinolizinesRatsRats, Sprague-DawleySignal TransductionToll-Like Receptor 4AlkaloidsInterleukin-1betaMatrinesMatrix MetalloproteinasesNF-kappa BoxymatrineQuinolizinesTlr4 protein, ratToll-Like Receptor 4Inflammationintervertebral disc degenerationoxymatrineTLR4/NF-κB signaling pathway

Identifiers

PMID31979980
PMCPMC7158602
OpenAlexW3002071829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.