Evidence map›Paper›PMID 31979417›Full record

ArticleInternational journal of molecular sciences2020

Chrysin Modulates Genes Related to Inflammation, Tissue Remodeling, and Cell Proliferation in the Gastric Ulcer Healing.

Felipe Leonardo Fagundes, Graziele de Morais Piffer, Larissa Lucena Périco, Vinicius Peixoto Rodrigues, Clélia Akiko Hiruma-Lima, Raquel de Cássia Dos Santos

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  4. The effect of chrysin on ischemia-reperfusion injury in the rat epigastric artery skin island flap.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Felipe Leonardo FagundesPost Graduate Program in Health Sciences, São Francisco University, Bragança Paulista, SP CEP 129160-400, Brazil.
Graziele de Morais PifferPost Graduate Program in Health Sciences, São Francisco University, Bragança Paulista, SP CEP 129160-400, Brazil.
Larissa Lucena PéricoSnyder Institute of Chronic Disease, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Vinicius Peixoto RodriguesDepartment of Physiology, São Paulo State University "Júlio de Mesquita Filho"-UNESP, Biosciences Institute, Botucatu, SP CEP 18618-689, Brazil.
Clélia Akiko Hiruma-LimaDepartment of Physiology, São Paulo State University "Júlio de Mesquita Filho"-UNESP, Biosciences Institute, Botucatu, SP CEP 18618-689, Brazil.
Raquel de Cássia Dos SantosPost Graduate Program in Health Sciences, São Francisco University, Bragança Paulista, SP CEP 129160-400, Brazil.
Universidade São Francisco · BRUniversidade Estadual Paulista (Unesp) · BRUniversity of Calgary · CA

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 16/21102-4
6 · The paper itself

Abstract

Chrysin exhibits anti-inflammatory and antioxidant activities. Here, the gastroprotective effect of chrysin was investigated in mouse models of gastric ulcer induced by absolute ethanol, acetic acid, and ischemia-reperfusion injury. The gastric-healing effect was evaluated at 7 and 14 days after treatment; the mechanism of action was verified using the expression of metalloproteinase 2 (

Indexed as

Acetic AcidAnimalsAnti-Ulcer AgentsApoptosisCaspase 3CatalaseCell ProliferationCyclooxygenase 1Cyclooxygenase 2Epidermal Growth FactorEthanolFlavonoidsGastric MucosaGene Expression RegulationInflammationInterleukin-10Acetic AcidAnti-Ulcer AgentsCaspase 3CatalasechrysinCyclooxygenase 1Cyclooxygenase 2Epidermal Growth FactorEthanolFlavonoidsIL10 protein, mouseInterleukin-10Matrix Metalloproteinase 2Matrix Metalloproteinase 9Membrane ProteinsPlant ExtractsPtgs1 protein, mousePtgs2 protein, mousechrysingastric ulcergastroprotective effecttissue remodeling, healing

Identifiers

PMID31979417
PMCPMC7038074
OpenAlexW3002119860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.