Evidence map›Paper›PMID 31979380›Full record

ArticleToxins2020

Diet Breadth Mediates the Prey Specificity of Venom Potency in Snakes.

Keith Lyons, Michel M Dugon, Kevin Healy

Abstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Paralysis efficiency (PDToxicon: X · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Frontiers in pharmacology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prey Shifts Drive Venom Evolution in Cone Snails.Molecular biology and evolution · 2024
    Article
  16. Article
  17. Inhibition of bacterial biofilms by the snake venom proteome.Biotechnology reports (Amsterdam, Netherlands) · 2023
    Article
  18. Article
  19. Article
  20. Venom phenotype conservation suggests integrated specialization in a lizard-eating snake.Toxicon : official journal of the International Society on Toxinology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Keith LyonsRyan Institute, School of Natural Sciences, National University of Ireland Galway, H91 R8EC Galway, Ireland.
Michel M DugonRyan Institute, School of Natural Sciences, National University of Ireland Galway, H91 R8EC Galway, Ireland.
Kevin HealyRyan Institute, School of Natural Sciences, National University of Ireland Galway, H91 R8EC Galway, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venoms are best known for their ability to incapacitate prey. In predatory groups, venom potency is predicted to reflect ecological and evolutionary drivers relating to diet. While venoms have been found to have preyspecific potencies, the role of diet breadth on venom potencies has yet to be tested at large macroecological scales. Here, using a comparative analysis of 100 snake species, we show that the evolution of prey-specific venom potencies is contingent on the breadth of a species' diet. We find that while snake venom is more potent when tested on species closely related to natural prey items, we only find this prey-specific pattern in species with taxonomically narrow diets. While we find that the taxonomic diversity of a snakes' diet mediates the prey specificity of its venom, the species richness of its diet was not found to affect these prey-specific potency patterns. This indicates that the physiological diversity of a species' diet is an important driver of the evolution of generalist venom potencies. These findings suggest that the venoms of species with taxonomically diverse diets may be better suited to incapacitating novel prey species and hence play an important role for species within changing environments.

Indexed as

Predatory BehaviorSnakesAnimalsDietLethal Dose 50PhylogenySnake VenomsSnake Venomsdietdiet breadthLD50phylogenetic comparative analysesphylogenetic comparative biologypotencypredatorprey-specificsnakesvenom

Identifiers

PMID31979380
PMCPMC7076792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.