Evidence map›Paper›PMID 31979350›Full record

ArticleMolecules (Basel, Switzerland)2020

Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures.

Julian Cardinal von Widdern, Tim Hohmann, Faramarz Dehghani

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Role of Cannabinoids in Inflammation.Molecules (Basel, Switzerland) · 2022
    Article
  10. The effects ofPeerJ · 2022
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Julian Cardinal von WiddernDepartment of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, 06097 Halle (Saale), Germany.
Tim HohmannDepartment of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, 06097 Halle (Saale), Germany.
Faramarz DehghaniDepartment of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, 06097 Halle (Saale), Germany.
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal cannabidiol (abn-CBD) exerts neuroprotective effects in vivo and in vitro. In the present study, we investigated the impact of abn-CBD on the glial production of proinflammatory mediators and scar formation within in vitro models. Primary astrocytic-microglial cocultures and astrocytic cultures from neonatal C57BL/6 mice and CB

Indexed as

AnimalsAstrocytesCannabinoidsCoculture TechniquesInflammationInflammation MediatorsInterleukin-6LipopolysaccharidesMiceMice, Inbred C57BLMice, KnockoutMicrogliaNeuroprotective AgentsNitric OxideReceptor, Cannabinoid, CB2Resorcinols4-(3-3,4-p-menthadien-(1,8)-yl)olivetolCannabinoidsInflammation MediatorsInterleukin-6LipopolysaccharidesNeuroprotective AgentsNitric OxideReceptor, Cannabinoid, CB2ResorcinolsTumor Necrosis Factor-alphaabnormal cannabidiolastrocytescannabinoid ligandsinflammationinterleukin-6microglianeuroinflammationnitric oxidesynthetic cannabinoidstumor necrosis factor α

Identifiers

PMID31979350
PMCPMC7037200
OpenAlexW3002765537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.