ReviewMolecules (Basel, Switzerland)2020
Biological Activities of Gedunin-A Limonoid from the Meliaceae Family.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Herbal Therapeutics for Alzheimer's Disease: Ancient Indian Medicine System from the Modern Viewpoint.Current neuropharmacology · 2023Pooled it
- Integrated in silico and in vitro assessment of Azadirachta indica leaf extract against multi-drug resistant Citrobacter koseri and Staphylococcus saprophyticus.Scientific reports · 2026Article
- Host and Parasite-Targeted Mechanisms of Gedunin Against Cutaneous Leishmaniasis: In Vitro and In Vivo Evaluation.Acta parasitologica · 2026Article
- Host and Parasite-Targeted Mechanisms of Gedunin Against Cutaneous Leishmaniasis: In Vitro and In Vivo Evaluation.Acta parasitologica · 2026Article
- Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review.Mini reviews in medicinal chemistry · 2026Review
- Comparative analysis of antioxidant and antimicrobial potentials of different extracts ofToxicology reports · 2025Article
- Chemical and Antiplasmodial Investigations onACS omega · 2025Article
- Neem (Food science & nutrition · 2025Review
- Insights into the Mechanism of Action of the Degraded Limonoid Prieurianin.International journal of molecular sciences · 2024Review
- Article
- Gedunin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine.Archives of medical science : AMS · 2024Article
- Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024Article
- Uncovering the Role of Natural and Synthetic Small Molecules in Counteracting the Burden of α-Synuclein Aggregates and Related Toxicity in Different Models of Parkinson's Disease.International journal of molecular sciences · 2023Review
- Extract of Bletilla formosana callus elevates cellular antioxidative activity via Nrf2/HO-1 signaling pathway and inhibits melanogenesis in zebrafish.Journal, genetic engineering & biotechnology · 2023Article
- Antimalarial and Cytotoxic Activity of Native Plants Used in Cabo Verde Traditional Medicine.Plants (Basel, Switzerland) · 2023Article
- Bioactive limonoids fromCurrent research in toxicology · 2023Article
- LC-MS Analysis, Computational Investigation, and Antimalarial Studies ofBioinformatics and biology insights · 2023Article
- Determination and Quantification of Phytochemicals from the Leaf Extract ofPlants (Basel, Switzerland) · 2022Article
- Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells.Molecules (Basel, Switzerland) · 2022Article
- Documentation of Phytotoxic Compounds Existing inToxins · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Several biological activities have been attributed to gedunin, including antibacterial, insecticidal, antimalarial, antiallergic, anti-inflammatory, anticancer, and neuroprotective effects. The discovery of gedunin as a heat shock protein (Hsp) inhibitor represented a very important landmark for its application as a biological therapeutic agent. The current study is a critical literature review based on the several biological activities so far described for gedunin, its therapeutic effect on some human diseases, and future directions of research for this natural compound.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.