Evidence map›Paper›PMID 31979218›Full record

ArticleCancers2020

CD44 Targeting Mediated by Polymeric Nanoparticles and Combination of Chlorine TPCS

Elisa Gaio, Claudia Conte, Diletta Esposito, Elena Reddi, Fabiana Quaglia, Francesca Moret

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 63 citations in OpenAlex.

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  19. Novel Thieno [2,3-International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elisa GaioDepartment of Biology, University of Padova, 35121 Padova, Italy.
Claudia ConteDrug Delivery Laboratory, Department of Pharmacy, University of Napoli Federico II, 80131 Napoli, Italy.
Diletta EspositoDrug Delivery Laboratory, Department of Pharmacy, University of Napoli Federico II, 80131 Napoli, Italy.
Elena ReddiDepartment of Biology, University of Padova, 35121 Padova, Italy.
Fabiana QuagliaDrug Delivery Laboratory, Department of Pharmacy, University of Napoli Federico II, 80131 Napoli, Italy.
Francesca MoretDepartment of Biology, University of Padova, 35121 Padova, Italy.
University of Naples Federico II · ITUniversity of Padua · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG2014 #15764Department of Biology, University of Padova PRIDseed2018
6 · The paper itself

Abstract

The presence of rare but highly tumorigenic cancer stem cells (CSCs) within the tumors is recognized as one of the major reasons of failure of conventional chemotherapies, mainly attributed to the development of drug resistance and increasing metastatic potential. Here, we propose a therapeutic strategy based on the simultaneous delivery of docetaxel (DTX) and the photosensitizer meso-tetraphenyl chlorine disulfonate (TPCS

Indexed as

cancer stem cellschemotherapycombination therapyhyaluronic acidmammospheresphotodynamic therapytargeted nanoparticles

Identifiers

PMID31979218
PMCPMC7072409
OpenAlexW3001290667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.