Evidence map›Paper›PMID 31979185›Full record

ArticleCells2020

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

Lili Yue, Liuqing Wang, Yangchun Du, Wei Zhang, Kozo Hamada, Yoshifumi Matsumoto, Xi Jin, Yandong Zhou, Katsuhiko Mikoshiba, Donald L Gill and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  13. NLRP3-Mediated Inflammation in Atherosclerosis and Associated Therapeutics.Frontiers in cell and developmental biology · 2022
    Review
  14. IPContact (Thousand Oaks (Ventura County, Calif.))
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Lili YueBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Liuqing WangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Yangchun DuBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Wei ZhangDepartment of Molecular and Cellular Biology, College of Biological Science, University of Guelph, 50 Stone Rd E, Guelph, ON N1G 2W1, Canada.
Kozo HamadaShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Yoshifumi MatsumotoLaboratory for Developmental Neurobiology, Center for Brain Sciences, RIKEN, 2-1 Hirosawa, Wako, Saitam 351-0198, Japan.
Xi JinBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Yandong ZhouDepartment of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Katsuhiko MikoshibaShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Donald L GillDepartment of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Shengcheng HanBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Youjun WangBeijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Beijing Normal University · CNPennsylvania State University · USShanghaiTech University · CNCentral Institute for Experimental Animals · JPUniversity of Guelph · CA

Funding

Understanding Store-Operated Calcium Signal TransductionR35GM131916 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GILL, DONALD L · 2019 to 2023
$2.9M
NIGMS NIH HHS R35 GM131916
6 · The paper itself

Abstract

Being the largest the Ca

Indexed as

CalciumCalcium SignalingCell MovementCell ProliferationEndoplasmic ReticulumHEK293 CellsHumansInositol 1,4,5-Trisphosphate ReceptorsNedd4 Ubiquitin Protein LigasesORAI1 ProteinProtein IsoformsCalciumInositol 1,4,5-Trisphosphate ReceptorsNedd4L protein, humanNedd4 Ubiquitin Protein LigasesORAI1 ProteinProtein IsoformscalciumIP3RNEDD4LOrai1SERCAstore-operated Ca2+ entry

Identifiers

PMID31979185
PMCPMC7072192
OpenAlexW3001936787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.