Evidence map›Paper›PMID 31979029›Full record

ArticleBiomolecules2020

The Contribution of IgG Glycosylation to Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement-Dependent Cytotoxicity (CDC) in Hashimoto's Thyroiditis: An in Vitro Model of Thyroid Autoimmunity.

Marta Ząbczyńska, Katarzyna Polak, Kamila Kozłowska, Grzegorz Sokołowski, Ewa Pocheć

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Study on antibody Fc-glycosylation for optimal effector functions.Chemical communications (Cambridge, England) · 2023
    Article
  9. Review
  10. Article
  11. The role ofFrontiers in immunology · 2023
    Review
  12. Review
  13. Review
  14. Changes of IgGFrontiers in immunology · 2022
    Article
  15. The Frequency of CD4International journal of endocrinology and metabolism · 2021
    Article
  16. Review
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  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marta ZąbczyńskaDepartment of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Katarzyna PolakDepartment of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Kamila KozłowskaDepartment of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Grzegorz SokołowskiDepartment of Endocrinology, University Hospital in Kraków, Kopernika 17, 31-501 Kraków, Poland.
Ewa PochećDepartment of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Gronostajowa 9, 30-387 Kraków, Poland.
Jagiellonian University · PLKrakow Cardiovascular Research Institute · PL

Funding

Narodowe Centrum Nauki 2015/18/E/NZ6/00602Uniwersytet Jagielloński w Krakowie K/DSC/002996, K/DSC/003987
6 · The paper itself

Abstract

Antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) are involved in destruction of thyroid tissue in Hashimoto's thyroiditis (HT).

Indexed as

Antibody-Dependent Cell CytotoxicityAutoantibodiesAutoimmunityCell Line, TumorComplement System ProteinsGlycoproteinsGlycosylationHashimoto DiseaseHL-60 CellsHumansImmunoglobulin GLectinsLeukocytes, MononuclearPolysaccharidesSialic AcidsThyroid Epithelial CellsAutoantibodiesComplement System ProteinsGlycoproteinsglycosylated IgGImmunoglobulin GLectinsPolysaccharidesSialic Acidsantibody-dependent cell-mediated cytotoxicity (ADCC)complement-dependent cyttoxicity (CDC)Hashimoto’s thyroiditisIgGN-glycosylationsialylation

Identifiers

PMID31979029
PMCPMC7072644
OpenAlexW3002083228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.