Evidence map›Paper›PMID 31979011›Full record

ArticleNutrients2020

Expression Patterns of Muscle-Specific miR-133b and miR-206 Correlate with Nutritional Status and Sarcopenia.

Francesca Iannone, Alberto Montesanto, Erika Cione, Paolina Crocco, Maria Cristina Caroleo, Serena Dato, Giuseppina Rose, Giuseppe Passarino

Registry-linked trialOpen access · goldAbstract readEvaluation Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05878106 (Creatine Supplementation and Resistance Training in Patients With Breast Cancer), which is not on this map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05878106 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)

TypeinterventionalSponsorUniversity of DeustoRan2024 to 2025Enrolled120ConditionsBreast Cancer, Supplementation, Resistance Training, Physical PerformanceArmsCreatine supplementation, Resistance training
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Role of microRNA-22 in Metabolism.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Determination of AGE-CML Level in Commercially Available Sports Bar in Italy.Recent advances in food, nutrition & agriculture · 2025
    Article
  12. Review
  13. Article
  14. The Role of MicroRNA in the Pathogenesis of Duchenne Muscular Dystrophy.International journal of molecular sciences · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Contribution of skeletal muscle-specific microRNA-133b to insulin resistance in heart failure.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  20. miR-424(322)-5p targetsActa biochimica et biophysica Sinica · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Francesca IannoneDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Alberto MontesantoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Erika CioneDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
Paolina CroccoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Maria Cristina CaroleoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
Serena DatoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Giuseppina RoseDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Giuseppe PassarinoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
University of Calabria · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 20157ATSLF
6 · The paper itself

Abstract

Sarcopenia and malnutrition are commonly occurring conditions in the elderly that frequently coexist, leading to substantial effects on morbidity/mortality. Evidence established muscle-specific microRNAs (miRNAs) or myomiRs as essential regulators of skeletal muscle processes, from myogenesis to muscle homeostasis. This study aimed to evaluate the association between myomiRs and sarcopenia and explore the potential of nutrition in mediating this association. qPCR was employed to characterize the myomiR-1, -133a/b, -206, -208b, and -499 expression profiles of 109 non-sarcopenic and 109 sarcopenic subjects. In our sample, the proportion malnourished or at-risk subjects was higher in sarcopenia (

Indexed as

AgedAged, 80 and overCase-Control StudiesFemaleGeriatric AssessmentHumansMaleMalnutritionMicroRNAsMuscle, SkeletalMuscle StrengthNutritional StatusNutrition AssessmentSarcopeniaMicroRNAsMIRN133 microRNA, humanMIRN206 microRNA, humanagingmiR-133bmiR-206muscle wastingmyomiRsnutritional statussarcopenia

Identifiers

PMID31979011
PMCPMC7071413
OpenAlexW3002308525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.