ArticlePharmaceutics2020
Design of New Polyaspartamide Copolymers for siRNA Delivery in Antiasthmatic Therapy.
Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 59 citations in OpenAlex.
- Enzymatically Cross-Linked Hydrogel Beads Based on a Novel Poly(aspartamide) Derivative.Gels (Basel, Switzerland) · 2025Article
- Design of Experiments Grants Mechanistic Insights into the Synthesis of Spermine-Containing PBAE Copolymers.ACS applied materials & interfaces · 2024Article
- Airway mucus in pulmonary diseases: Muco-adhesive and muco-penetrating particles to overcome the airway mucus barriers.International journal of pharmaceutics · 2023Review
- Galactosylated Polymer/Gold Nanorods Nanocomposites for Sustained and Pulsed Chemo-Photothermal Treatments of Hepatocarcinoma.Pharmaceutics · 2022Article
- Correlating Rheological Properties of a Gellan Gum-Based Bioink: A Study of the Impact of Cell Density.Polymers · 2022Article
- Nanocarriers for delivery of siRNA as gene silencing mediator.EXCLI journal · 2022Review
- Long Noncoding RNA Hotair Promotes the Progression and Immune Escape in Laryngeal Squamous Cell Carcinoma through MicroRNA-30a/GRP78/PD-L1 Axis.Journal of immunology research · 2022Article
- Stimuli-Responsive Poly(aspartamide) Derivatives and Their Applications as Drug Carriers.International journal of molecular sciences · 2021Review
- Development of New Targeted Inulin Complex Nanoaggregates for siRNA Delivery in Antitumor Therapy.Molecules (Basel, Switzerland) · 2021Article
- Drug Delivery of siRNA Therapeutics.Pharmaceutics · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here, a novel protonable copolymer was realized for the production of polyplexes with a siRNA (inhibitor of STAT6 expression in asthma), with the aim of a pulmonary administration. The polycation was synthesized by derivatization of α,β-poly(N-2-hydroxyethyl)d,l-aspartamide (PHEA) with 1,2-Bis(3-aminopropylamino)ethane (bAPAE) in proper conditions to obtain a PHEA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.