Evidence map›Paper›PMID 31978961›Full record

ArticleMaterials (Basel, Switzerland)2020

3D Printing of Polycaprolactone-Polyaniline Electroactive Scaffolds for Bone Tissue Engineering.

Arie Wibowo, Cian Vyas, Glen Cooper, Fitriyatul Qulub, Rochim Suratman, Andi Isra Mahyuddin, Tatacipta Dirgantara, Paulo Bartolo

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arie WibowoMaterial Science and Engineering Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, 40132 Bandung, Indonesia.
Cian VyasDepartment of Mechanical, Aerospace, and Civil Engineering, University of Manchester, Manchester, M13 9PL, UK.
Glen CooperDepartment of Mechanical, Aerospace, and Civil Engineering, University of Manchester, Manchester, M13 9PL, UK.
Fitriyatul QulubMaterial Science and Engineering Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, 40132 Bandung, Indonesia.
Rochim SuratmanMaterial Science and Engineering Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, 40132 Bandung, Indonesia.
Andi Isra MahyuddinMechanical Design Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, 40132 Bandung, Indonesia.
Tatacipta DirgantaraLightweight Structure Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, 40132 Bandung, Indonesia.
Paulo BartoloDepartment of Mechanical, Aerospace, and Civil Engineering, University of Manchester, Manchester, M13 9PL, UK.

Funding

Indonesian Ministry for Research, Technology and Higher Education Overseas Collaboration Research Fund 436.11/I1.C08/PL-DIKTI/2018United Kingdom's Engineering and Physical Sciences Research Council (EPSRC) and Medical Research Council (MRC) Centre for Doctoral Training in Regenerative Medicine EP/L014904/1
6 · The paper itself

Abstract

Electrostimulation and electroactive scaffolds can positively influence and guide cellular behaviour and thus has been garnering interest as a key tissue engineering strategy. The development of conducting polymers such as polyaniline enables the fabrication of conductive polymeric composite scaffolds. In this study, we report on the initial development of a polycaprolactone scaffold incorporating different weight loadings of a polyaniline microparticle filler. The scaffolds are fabricated using screw-assisted extrusion-based 3D printing and are characterised for their morphological, mechanical, conductivity, and preliminary biological properties. The conductivity of the polycaprolactone scaffolds increases with the inclusion of polyaniline. The in vitro cytocompatibility of the scaffolds was assessed using human adipose-derived stem cells to determine cell viability and proliferation up to 21 days. A cytotoxicity threshold was reached at 1% wt. polyaniline loading. Scaffolds with 0.1% wt. polyaniline showed suitable compressive strength (6.45 ± 0.16 MPa) and conductivity (2.46 ± 0.65 × 10

Indexed as

3D printingelectroactive scaffoldpolyanilinetissue engineering

Identifiers

PMID31978961
PMCPMC7040705

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.